Evidence map›Paper›PMID 23804596›Full record

ArticlePediatric pulmonology2014

Secondhand smoke exposure in preterm infants with bronchopulmonary dysplasia.

Joseph M Collaco, Angela D Aherrera, Timothy Ryan, Sharon A McGrath-Morrow

Open access · greenAbstract read
In one paragraph

Article in Pediatric pulmonology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Long-term pulmonary outcomes in BPD throughout the life-course.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  2. Review
  3. Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Influences of environmental exposures on preterm lung disease.Expert review of respiratory medicine · 2021
    Review
  10. Article
  11. Review
  12. Article
  13. Observational
  14. Urine Cotinine Screening Detects Nearly Ubiquitous Tobacco Smoke Exposure in Urban Adolescents.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joseph M CollacoEudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Angela D Aherrera
Timothy Ryan
Sharon A McGrath-Morrow
Johns Hopkins University · US

Funding

Multidisciplinary Training Program in Pediatric PulmonaryT32HL072748 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Joseph Michael Collaco · 2003 to 2026
$6.1M
Resolution of Diffuse Inflammatory Lung Injury in Neonatal MiceR01HL114800 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MCGRATH-MORROW, SHARON ANN · 2013 to 2021
$3.3M
NHLBI NIH HHS R01 HL114800NHLBI NIH HHS T32 HL072748
6 · The paper itself

Abstract

objectivesPreterm infants and children with bronchopulmonary dysplasia (BPD) often experience significant respiratory morbidities during the first two years of life. Second hand smoke (SHS) has been demonstrated to lead to respiratory morbidities in the general population. The objectives of this study were to assess the prevalence/impact of SHS on preterm infants and children with BPD.

methodsSubjects (n = 352) were recruited from the Johns Hopkins BPD outpatient clinic between January 2008 and August 2012. Second hand smoke exposure and respiratory morbidities were assessed through questionnaires and chart review.

resultsTwenty-eight percent of preterm infants with BPD were exposed to SHS in the home setting, despite having significant lung disease. SHS was associated with multiple measures of socio-economic status, including lower household income (P < 0.001), lower caregiver education level (P = 0.013), and having public versus private insurance (P = 0.002). We found no difference in acute care use or chronic symptoms with SHS exposure. We observed trends that preterm infants who were exposed to SHS were more likely to be prescribed inhaled corticosteroids (P = 0.054) and were weaned off of supplemental oxygen over 2 months later (P = 0.13) than infants not exposed to SHS.

conclusionSHS exposure in preterm infants with BPD is common, even in those receiving supplemental oxygen and respiratory medications. Although there were no associations between respiratory outcomes and self-reported SHS exposure, trends toward increased use of inhaled steroids and a longer duration of supplemental oxygen use were noted. Further work is needed to determine more accurate means of assessing SHS risk in this vulnerable population.

Indexed as

Bronchopulmonary DysplasiaAdrenal Cortex HormonesAnti-Inflammatory AgentsCombined Modality TherapyEnvironmental ExposureFemaleFollow-Up StudiesHospitalizationHumansInfantInfant, NewbornInfant, PrematureKaplan-Meier EstimateLogistic ModelsMaleOxygen Inhalation TherapyAdrenal Cortex HormonesAnti-Inflammatory AgentsTobacco Smoke Pollutionbronchopulmonary dysplasiachronic lung diseaseenvironmental tobacco smokeprematuritysecondhand smoke

Identifiers

PMID23804596
PMCPMC4052435
OpenAlexW1559042743

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.