Evidence map›Paper›PMID 23804569›Full record

ArticleThe Journal of general virology2013

Diversity of picornaviruses in rural Bolivia.

W Allan Nix, Nino Khetsuriani, Silvia Peñaranda, Kaija Maher, Linda Venczel, Zsuzsa Cselkó, Maria Cecilia Freire, Daniel Cisterna, Cristina L Lema, Patricia Rosales and 6 more

Abstract read
In one paragraph

Article in The Journal of general virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 56 citations in OpenAlex.

  1. Journal of virology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

W Allan NixCenters for Disease Control and Prevention, Atlanta, GA, USA.
Nino KhetsurianiCenters for Disease Control and Prevention, Atlanta, GA, USA.
Silvia PeñarandaCenters for Disease Control and Prevention, Atlanta, GA, USA.
Kaija MaherCenters for Disease Control and Prevention, Atlanta, GA, USA.
Linda VenczelCenters for Disease Control and Prevention, Atlanta, GA, USA.
Zsuzsa CselkóCenters for Disease Control and Prevention, Atlanta, GA, USA.
Maria Cecilia FreireInstituto Nacional de Enfemedades Infecciosos C. Malbrán, Buenos Aires, Argentina.
Daniel CisternaInstituto Nacional de Enfemedades Infecciosos C. Malbrán, Buenos Aires, Argentina.
Cristina L LemaInstituto Nacional de Enfemedades Infecciosos C. Malbrán, Buenos Aires, Argentina.
Patricia RosalesMinistry of Health and Sports, La Paz, Bolivia.
Jacqueline R RodriguezPediatric Hospital San Antonio de Los Sauces, Monteagudo, Bolivia.
Wilma RodriguezMinistry of Health and Sports, La Paz, Bolivia.
Percy HalkyerPan-American Health Organization, La Paz, Bolivia.
Olivier RonveauxPan-American Health Organization, La Paz, Bolivia.
Mark A PallanschCenters for Disease Control and Prevention, Atlanta, GA, USA.
M Steven ObersteCenters for Disease Control and Prevention, Atlanta, GA, USA.
Centers for Disease Control and Prevention · USAdministración Nacional de Laboratorios e Institutos de Salud · ARPan American Health Organization (Cuba) · CU

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

The family Picornaviridae is a large and diverse group of viruses that infect humans and animals. Picornaviruses are among the most common infections of humans and cause a wide spectrum of acute human disease. This study began as an investigation of acute flaccid paralysis (AFP) in a small area of eastern Bolivia, where surveillance had identified a persistently high AFP rate in children. Stools were collected and diagnostic studies ruled out poliovirus. We tested stool specimens from 51 AFP cases and 34 healthy household or community contacts collected during 2002-2003 using real-time and semi-nested reverse transcription polymerase chain reaction assays for enterovirus, parechovirus, cardiovirus, kobuvirus, salivirus and cosavirus. Anecdotal reports suggested a temporal association with neurological disease in domestic pigs, so six porcine stools were also collected and tested with the same set of assays, with the addition of an assay for porcine teschovirus. A total of 126 picornaviruses were detected in 73 of 85 human individuals, consisting of 53 different picornavirus types encompassing five genera (all except Kobuvirus). All six porcine stools contained porcine and/or human picornaviruses. No single virus, or combination of viruses, specifically correlated with AFP; however, the study revealed a surprising complexity of enteric picornaviruses in a single community.

Indexed as

AdolescentAnimalsBoliviaChildChild, PreschoolFecesFemaleHumansInfantMaleMolecular EpidemiologyMolecular Sequence DataParaplegiaPicornaviridaePicornaviridae InfectionsReal-Time Polymerase Chain Reaction

Identifiers

PMID23804569
PMCPMC4637931
OpenAlexW1983008158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.