ArticleObesity (Silver Spring, Md.)2014
Ethnic differences in the effects of hepatic fat deposition on insulin resistance in nonobese middle school girls.
Article in Obesity (Silver Spring, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Hepatic Fat in Early Childhood Is Independently Associated With Estimated Insulin Resistance: The Healthy Start Study.The Journal of clinical endocrinology and metabolism · 2021Article
- Body composition and insulin resistance in children.European journal of clinical nutrition · 2018Review
- Salivary Cortisol Does Not Correlate with Metabolic Syndrome Markers or Subjective Stress in Overweight Children.Journal of childhood obesity · 2018Article
- Ethnic and Sex Differences in Adiponectin: From Childhood to Adulthood.The Journal of clinical endocrinology and metabolism · 2016Article
- Quantitative Imaging Biomarkers of NAFLD.Digestive diseases and sciences · 2016Review
- Sex Hormone-Binding Globulin in Children and Adolescents.Journal of clinical research in pediatric endocrinology · 2016Review
- In Nonobese Girls, Waist Circumference as a Predictor of Insulin Resistance Is Comparable to MRI Fat Measures and Superior to BMI.Hormone research in paediatrics · 2015Article
- Predicting hepatic steatosis in a racially and ethnically diverse cohort of adolescent girls.The Journal of pediatrics · 2014Article
- Adolescent Obesity and Its Risks: How to Screen and When to Refer.Journal of clinical outcomes management : JCOM · 2014Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveIn nonobese youth, to investigate whether hepatic fat deposition and its metabolic consequences vary between ethnic groups. DESIGN AND
methodsThirty-two nonobese girls (12 Hispanic White [H] and 20 non-Hispanic White [NHW] girls), aged 11-14 years old were recruited. Outcome measures were MRI measured hepatic proton density fat fraction (hepatic PDFF), BMI Z-score, waist circumference, fasting insulin, glucose, adiponectin, sex hormone-binding globulin [SHBG], ALT, AST, triglycerides, and HOMA-IR.
resultsThere were no significant differences in mean BMI Z-scores (P = 0.546) or hepatic PDFF (P = 0.275) between H and NHW girls; however, H girls showed significant correlations between hepatic PDFF and markers of IR (fasting insulin, HOMA-IR, adiponectin, SHBG, triglycerides; all P < 0.05), while NHW girls showed no significant correlations. Matched by hepatic PDFF or BMI Z-score, H girls had more evidence of IR for a given hepatic PDFF (mean insulin, HOMA-IR, and SHBG; all P < 0.05) or BMI Z-score (mean insulin and HOMA-IR; all P < 0.01) than NHW girls.
conclusionsIn nonobese female youth, ethnicity-related differences in effects of hepatic fat on IR are evident, so that in H girls, a given amount of hepatic fat appears to result in a more predictable and greater degree of IR than in NHW girls.
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