Evidence map›Paper›PMID 23804406›Full record

ArticleJournal of pediatric psychology2013

Development and reliability of a correction factor for family-reported medication adherence: pediatric inflammatory bowel disease as an exemplar.

Yelena P Wu, Ahna L H Pai, Wendy N Gray, Lee A Denson, Kevin A Hommel

Abstract readComparative Study
In one paragraph

Article in Journal of pediatric psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Medication adherence in youths with CKD: habits for success.Pediatric nephrology (Berlin, Germany) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yelena P WuDivision of Behavioral Medicine and Clinical Psychology, Center for Adherence and Self-Management, MLC-7039, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Ahna L H Pai
Wendy N Gray
Lee A Denson
Kevin A Hommel

Funding

Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Theresa Alenghat · 2007 to 2026
$24.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2012 to 2014
$9.9M
Behavioral Treatment of Nonadherence in Pediatric Inflammatory Bowel DiseaseK23DK079037 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI HOMMEL, KEVIN · 2007 to 2011
$618k
NCRR NIH HHS UL1RR026314NIDDK NIH HHS K23 DK079037NIDDK NIH HHS P30 DK 078392
6 · The paper itself

Abstract

objectivesTo examine the issue of accurate adherence assessment and illustrate methodologies for correcting parent-reported medication adherence.

methods40 children with inflammatory bowel disease provided medication adherence data using electronic monitoring. Parents provided subjective reports of medication adherence. Receiver operating characteristic analyses were used to examine the detection of non-adherence at several adherence cut-points. 2 methods for empirically deriving a correction factor for subjectively reported adherence were applied.

resultsAlthough parent-report and EM adherence were significantly correlated, parent-reported adherence was significantly higher than EM adherence. A 90% cut-point provided the highest sensitivity and specificity. Both correction factors reliably adjusted parent-reported adherence based on EM adherence.

conclusionsApplication of an empirically derived correction factor for parent-reported adherence using methodologies, such as those illustrated in the current study, could yield more accurate adherence assessment. Obtaining more accurate adherence assessments based on parent-report will have implications for self-management interventions, clinician prescribing behavior, and medication safety.

Indexed as

Drug MonitoringAdolescentChildFamilyFemaleHumansInflammatory Bowel DiseasesLab-On-A-Chip DevicesMalePsychometricsReproducibility of ResultsSensitivity and SpecificitySurveys and Questionnairescompliancemeasurementmedication-takingnonadherenceself-management

Identifiers

PMID23804406
PMCPMC3859234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.