Evidence map›Paper›PMID 23804163›Full record

ArticleJournal of biomedical optics2013

Motion-contrast laser speckle imaging of microcirculation within tissue beds in vivo.

Rong Liu, Jia Qin, Ruikang K Wang

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rong LiuUniversity of Washington, Department of Bioengineering, Seattle, Washington 98195, China.
Jia Qin
Ruikang K Wang

Funding

OPTICAL MICROANGIOGRAHY OF CEREBROVASCULAR PERFUSIONR01HL093140 · NHLBI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2008 to 2017
$4.2M
Volumetric imaging of blood perfusion and tissue morphology in the cochleaR01DC010201 · NIDCD · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2013
$2.2M
Label-free optical imaging of 3D structural and functional microcirculationsR01EB009682 · NIBIB · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2012
$1.7M
NHLBI NIH HHS R01 HL093140NHLBI NIH HHS R01HL093140NHLBI NIH HHS R01HL093140SNIBIB NIH HHS R01 EB009682NIBIB NIH HHS R01EB009682NIDCD NIH HHS R01 DC010201NIDCD NIH HHS R01DC01201
6 · The paper itself

Abstract

Laser speckle imaging is widely used to monitor functional blood perfusion within tissue beds in vivo but traditionally has difficulty visualizing small blood vessels even when the exposure time of the detector is long. We report a simple method that uses the motion contrast of dynamic speckle patterns to noninvasively visualize the distribution of blood flow within tissue beds in vivo. We experimentally demonstrate that the motion contrast can significantly suppress the effect of static scattering, leading to enhanced visibility of the functional blood vessels, including capillaries when compared to the traditional laser speckle contrast imaging.

Indexed as

AnimalsBlood Flow VelocityCalibrationCapillariesCerebrovascular CirculationContrast MediaDiagnostic ImagingEarEquipment DesignHemodynamicsLasersMiceMicrocirculationMotionScattering, RadiationTime FactorsContrast Media

Identifiers

PMID23804163
PMCPMC3693037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.