ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2013
Distinct familiarity-based response patterns for faces and buildings in perirhinal and parahippocampal cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Article
- Complementary roles of the human perirhinal and the entorhinal cortex in the hippocampal retrieval of episodic memory.iScience · 2025Article
- Brief Encounters with Real Objects Modulate the Medial Parietal But Not Occipitotemporal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Engrams Formed in Virtual Reality Exhibit Reduced Familiarity Upon Retrieval: Electrophysiological Correlates of Source Memory Retrieval Indicate Modality-Dependent Differences in Recognition Memory.The European journal of neuroscience · 2025Article
- The role of recollection, familiarity, and the hippocampus in episodic and working memory.Neuropsychologia · 2024Article
- Schemas provide a scaffold for neocortical integration of new memories over time.Nature communications · 2022Article
- Category-specific memory encoding in the medial temporal lobe and beyond: the role of reward.Learning & memory (Cold Spring Harbor, N.Y.) · 2022Article
- Functional Specialization of the Medial Temporal Lobes in Human Recognition Memory: Dissociating Effects of Hippocampal versus Parahippocampal Damage.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Article
- Dataset of human intracranial recordings during famous landmark identification.Scientific data · 2022Article
- Category Selectivity for Face and Scene Recognition in Human Medial Parietal Cortex.Current biology : CB · 2020Article
- Rapid and coarse face detection: With a lack of evidence for a nasal-temporal asymmetry.Attention, perception & psychophysics · 2020Article
- Altered functional connectivity of cortical networks in semantic variant Primary Progressive Aphasia.NeuroImage. Clinical · 2020Article
- Dopamine Related Genes Differentially Affect Declarative Long-Term Memory in Healthy Humans.Frontiers in behavioral neuroscience · 2020Article
- Behavioral and neural evidence of enhanced long-term memory for untrustworthy faces.Scientific reports · 2019Article
- Perirhinal circuits for memory processing.Nature reviews. Neuroscience · 2019Review
- Functional connectivity in category-selective brain networks after encoding predicts subsequent memory.Hippocampus · 2019Article
- Animacy and real-world size shape object representations in the human medial temporal lobes.Human brain mapping · 2018Article
- Integrative and distinctive coding of visual and conceptual object features in the ventral visual stream.eLife · 2018Article
- Dissociable contributions of thalamic nuclei to recognition memory: novel evidence from a case of medial dorsal thalamic damage.Learning & memory (Cold Spring Harbor, N.Y.) · 2018Article
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4 authors.
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Abstract
An unresolved question in our understanding of the medial temporal lobes is how functional differences between structures pertaining to stimulus category relate to the distinction between item-based and contextually based recognition-memory processes. Specifically, it remains unclear whether perirhinal cortex (PrC) supports item-based familiarity signals for all stimulus categories or whether parahippocampal cortex (PhC) may also play a role for stimulus categories that are known to engage this structure in other task contexts. Here, we used multivoxel pattern analyses of fMRI data to compare patterns of activity in humans that are associated with the perceived familiarity of faces, buildings, and chairs. During scanning, participants judged the familiarity of previously studied and novel items from all three categories. Instances in which recognition was based on recollection were removed from all analyses. In right PrC, we found patterns of activity that distinguished familiar from novel faces. By contrast, in right PhC, we observed such patterns for buildings. Familiarity signals for chairs were present in both structures but shared little overlap with the patterns observed for faces and buildings on a more fine-grained scale. In the hippocampus, we found no evidence for familiarity signals for any object category. Our findings show that both PrC and PhC contribute to the assessment of item familiarity. They suggest that PhC does not only represent episodic context but can also represent item information for some object categories in recognition-memory decisions. In turn, our findings also indicate that the involvement of PrC in representing item familiarity is not ubiquitous.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.