ArticleJournal of clinical microbiology1990
Characterization of the cellular antigens of Paracoccidioides brasiliensis yeast form.
Article in Journal of clinical microbiology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 28 citations in OpenAlex.
- Involvement of Dihydrolipoyl Dehydrogenase in the Phagocytosis and Killing ofFrontiers in microbiology · 2017Article
- Cell-free antigens from Paracoccidioides brasiliensis drive IL-4 production and increase the severity of paracoccidioidomycosis.PloS one · 2011Article
- Use of monoclonal antibodies in diagnosis of paracoccidioidomycosis: new strategies for detection of circulating antigens.Journal of clinical microbiology · 1997Article
- Immunological characterization of a recombinant 27-kilodalton antigenic protein from Paracoccidioides brasiliensis.Clinical and diagnostic laboratory immunology · 1996Article
- Paracoccidioidomycosis: an update.Clinical microbiology reviews · 1993Review
- Isolation and antigenicity of a 45-kilodalton Paracoccidioides brasiliensis immunodominant antigen.Infection and immunity · 1992Article
- Specific recognition pattern of IgM and IgG antibodies produced in the course of experimental paracoccidioidomycosis.Clinical and experimental immunology · 1992Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antigenic components of the yeast extract of Paracoccidioides brasiliensis Linder 2511 cultured for 3, 8, 20, 30, and 60 days were examined by the Western blot (immunoblot) technique. The 3-day extract was chosen for characterization of the antigenic components because its stability did not vary with time and it contained all antigens identified by patient sera. Antibodies to cross-reacting antigens of P. brasiliensis extracts were detected in sera from patients with histoplasmosis, candidiasis, and aspergillosis. The 58-, 57-, 21-, and 16-kilodalton (kDa) antigens were specific for P. brasiliensis, while the 48- and 45-kDa antigens were specific for paracoccidioidomycosis. The Western blot technique is a useful tool for the diagnosis of disease and revealed heterogeneity in the responses of patient sera. The combination of the 58-, 57-, and 45-kDa proteins confirmed a diagnosis of paracoccidioidomycosis (87% of the cases).
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