ArticleCell & bioscience2013
Specific structure and unique function define the hemicentin.
Article in Cell & bioscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
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- HMCN1 variants aggravate epidermolysis bullosa simplex phenotype.The Journal of experimental medicine · 2025Article
- Reduction of antisense transcription affects bovine leukemia virus replication and oncogenesis.PLoS pathogens · 2024Article
- Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2.Matrix biology : journal of the International Society for Matrix Biology · 2022Article
- Article
- Symbiosis maintenance in the facultative coral, Oculina arbuscula, relies on nitrogen cycling, cell cycle modulation, and immunity.Scientific reports · 2021Article
- Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.Scientific reports · 2021Article
- Role of Fibulins in Embryonic Stage Development and Their Involvement in Various Diseases.Biomolecules · 2021Review
- Complexities of the glomerular basement membrane.Nature reviews. Nephrology · 2021Review
- Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.Developmental dynamics : an official publication of the American Association of Anatomists · 2020Article
- The role of adhesion protein Fibulin7 in development and diseases.Molecular medicine (Cambridge, Mass.) · 2020Review
- Identification and Description of the Key Molecular Components of the Egg Strings of the Salmon Louse (Genes · 2019Article
- Transcriptional characterisation of the Exaiptasia pallida pedal disc.BMC genomics · 2019Article
- Tissue linkage through adjoining basement membranes: The long and the short term of it.Matrix biology : journal of the International Society for Matrix Biology · 2019Review
- Matrix mineralization controls gene expression in osteoblastic cells.Experimental cell research · 2018Article
- Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion.Developmental biology · 2016Article
- Liver-specific NG37 overexpression leads to diet-dependent fatty liver disease accompanied by cardiac dysfunction.Genes & nutrition · 2016Article
- ACAM, a novel member of the neural IgCAM family, mediates anterior neural tube closure in a primitive chordate.Developmental biology · 2016Article
- Soy glyceollins regulate transcript abundance in the female mouse brain.Functional & integrative genomics · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hemicentin has come a long way from when it was first identified in C. elegans as him-4 (High incidence of males). The protein is now a recognized player in maintaining the architectural integrity of vertebrate tissues and organs. Highly conserved hemicentin sequences across species indicate this gene's ancient evolutionary roots and functional importance. In mouse, hemicentin is liberally distributed on the cell surface of many cell types, including epithelial cells, endothelial cells of the eye, lung, and uterus, and trophectodermal cells of blastocyst. Recent discoveries have uncovered yet another vital purpose of hemicentin 1. The protein also serves a unique function in mitotic cytokinesis, during which this extracellular matrix protein plays a key role in cleavage furrow maturation. Though understanding of hemicentin function has improved through new discoveries, much about this protein remains mysterious.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.