Evidence map›Paper›PMID 23803158›Full record

ArticleMolecular microbiology2013

Competence and natural transformation in vibrios.

Yan Sun, Eryn E Bernardy, Brian K Hammer, Tim Miyashiro

Open access · greenAbstract read
In one paragraph

Article in Molecular microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Deployment of amBio · 2025
    Article
  4. Vibrio natriegens: Application of a Fast-Growing Halophilic Bacterium.Advances in biochemical engineering/biotechnology · 2025
    Review
  5. Article
  6. Public health aspects ofEFSA journal. European Food Safety Authority · 2024
    Article
  7. Deployment of abioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Regulators of natural competence in Vibrio parahaemolyticus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
  13. Nocturnal Acidification: A Coordinating Cue in theInternational journal of molecular sciences · 2022
    Review
  14. Article
  15. Control of Competence in Vibrio fischeri.Applied and environmental microbiology · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yan Sun *Department of Biochemistry and Molecular Biology Eberly College of Science The Pennsylvania State University 219 Wartik Lab University Park, PA 16802, USA.
Eryn E Bernardy *School of Biology Georgia Institute of Technology 310 Ferst Drive, Atlanta, GA 30332-0230.
Brian K HammerSchool of Biology Georgia Institute of Technology 310 Ferst Drive, Atlanta, GA 30332-0230.
Tim MiyashiroDepartment of Biochemistry and Molecular Biology Eberly College of Science The Pennsylvania State University 219 Wartik Lab University Park, PA 16802, USA.
Georgia Institute of Technology · USPennsylvania State University · US

Funding

Discovery of Small Molecule MBT Domain AntagonistsRC1GM090732 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRYE, STEPHEN VERNON · 2009 to 2010
$876k
Analysis of quorum-signaling crosstalk within the squid-vibrio symbiosisR00GM097032 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI MIYASHIRO, TIMOTHY · 2013 to 2015
$743k
NIGMS NIH HHS 4R00GM090732NIGMS NIH HHS R00 GM097032NIGMS NIH HHS RC1 GM090732
6 · The paper itself

Abstract

Natural transformation is a major mechanism of horizontal gene transfer in bacteria. By incorporating exogenous DNA elements into chromosomes, bacteria are able to acquire new traits that can enhance their fitness in different environments. Within the past decade, numerous studies have revealed that natural transformation is prevalent among members of the Vibrionaceae, including the pathogen Vibrio cholerae. Four environmental factors: (i) nutrient limitation, (ii) availability of extracellular nucleosides, (iii) high cell density and (iv) the presence of chitin, promote genetic competence and natural transformation in Vibrio cholerae by co-ordinating expression of the regulators CRP, CytR, HapR and TfoX respectively. Studies of other Vibrionaceae members highlight the general importance of natural transformation within this bacterial family.

Indexed as

DNA Transformation CompetenceGene Expression Regulation, BacterialGene Transfer, HorizontalInterspersed Repetitive SequencesRecombination, GeneticTransformation, BacterialVibrionaceae

Identifiers

PMID23803158
PMCPMC3820095
OpenAlexW1843353849

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.