Evidence map›Paper›PMID 23802859›Full record

ArticleBMC complementary and alternative medicine2013

Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification.

Fidele Ntie-Kang, Lydia Likowo Lifongo, Luc Meva'a Mbaze, Nnange Ekwelle, Luc C Owono Owono, Eugene Megnassan, Philip N Judson, Wolfgang Sippl, Simon M N Efange

Abstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
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  5. Frontiers in pharmacology · 2023
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  7. Anti-Onchocercal Properties of Extracts ofJournal of tropical medicine · 2022
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  8. Article
  9. Article
  10. Study of the Antimalarial Activity of the Leaf Extracts and Fractions ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Alkaloids from Plants with Antimalarial Activity: A Review of Recent Studies.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  16. Review
  17. Review
  18. Review
  19. Ethnomedicinal Plants Used by Traditional Healers to Treat Oral Health Problems in Cameroon.Evidence-based complementary and alternative medicine : eCAM · 2015
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fidele Ntie-KangChemical and Bioactivity Information Centre, Department of Chemistry, Faculty of Science, University of Buea, P. O. Box 63 Buea, Cameroon. ntiekfidele@gmail.com
Lydia Likowo Lifongo
Luc Meva'a Mbaze
Nnange Ekwelle
Luc C Owono Owono
Eugene Megnassan
Philip N Judson
Wolfgang Sippl
Simon M N Efange

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Cameroon herbs are traditionally used to meet health care needs and plans are on the way to integrate traditional medicine in the health care system, even though the plans have not been put into action yet. The country however has a rich biodiversity, with ~8,620 plant species, some of which are commonly used in the treatment of several microbial infections and a range of diseases (malaria, trypanosomiasis, leishmaniasis, diabetes and tuberculosis).

methodsOur survey consisted in collecting published data from the literature sources, mainly from PhD theses in Cameroonian university libraries and also using the author queries in major natural product and medicinal chemistry journals. The collected data includes plant sources, uses of plant material in traditional medicine, plant families, region of collection of plant material, isolated metabolites and type (e.g. flavonoid, terpenoid, etc.), measured biological activities of isolated compounds, and any comments on significance of isolated metabolites on the chemotaxonomic classification of the plant species. This data was compiled on a excel sheet and analysed.

resultsIn this study, a literature survey led to the collection of data on 2,700 secondary metabolites, which have been previously isolated or derived from Cameroonian medicinal plants. This represents distinct phytochemicals derived from 312 plant species belonging to 67 plant families. The plant species are investigated in terms of chemical composition with respect to the various plant families. A correlation between the known biological activities of isolated compounds and the ethnobotanical uses of the plants is also attempted. Insight into future direction for natural product search within the Cameroonian forest and Savanna is provided.

conclusionsIt can be verified that a phytochemical search of active secondary metabolites, which is inspired by knowledge from the ethnobotanical uses of medicinal plants could be very vital in a drug discovery program from plant-derived bioactive compounds.

Indexed as

CameroonDatabases, BibliographicEthnobotanyHumansMedicine, TraditionalPhytotherapyPlant ExtractsPlants, MedicinalPlant Extracts

Identifiers

PMID23802859
PMCPMC3703288

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.