ReviewKidney international2013
Recent advances in the noninvasive diagnosis of renal osteodystrophy.
Review in Kidney international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- The association between chronic kidney disease, falls, and fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Pooled it
- Article
- Leptin Is Associated with Testosterone, Nutritional Markers, and Vascular Muscular Dysfunction in Chronic Kidney Disease.International journal of molecular sciences · 2024Article
- Chronic Kidney Disease with Mineral Bone Disorder and Vascular Calcification: An Overview.Life (Basel, Switzerland) · 2024Review
- Update on imaging in chronic kidney disease-mineral and bone disorder: promising role of functional imaging.Skeletal radiology · 2022Review
- Vitamin D Insufficiency Prior to Paediatric Liver Transplantation Is Associated with Early T-Cell Mediated Rejection.Children (Basel, Switzerland) · 2021Article
- The Non-invasive Diagnosis of Bone Disorders in CKD.Calcified tissue international · 2021Review
- A retrospective study of end-stage kidney disease patients on maintenance hemodialysis with renal osteodystrophy-associated fragility fractures.BMC nephrology · 2021Article
- Digital radiography as an alternative method in the evaluation of bone density in uremic rats.Jornal brasileiro de nefrologia · 2020Article
- Assessment of Renal Osteodystrophy via Computational Analysis of Label-free Raman Detection of Multiple Biomarkers.Diagnostics (Basel, Switzerland) · 2020Article
- Hemiarthroplasty in the Hip Fracture Patient with Renal Impairment: To Cement or Not to Cement.Hip & pelvis · 2019Article
- Management of bone disease in cystinosis: Statement from an international conference.Journal of inherited metabolic disease · 2019Article
- Bone metabolism markers and hungry bone syndrome after parathyroidectomy in dialysis patients with secondary hyperparathyroidism.International urology and nephrology · 2019Article
- Raman Spectroscopic and Microscopic Analysis for Monitoring Renal Osteodystrophy Signatures.Biosensors · 2018Article
- Variations of parathyroid hormone and bone biomarkers are concordant only after a long term follow-up in hemodialyzed patients.Scientific reports · 2017Article
- Effects of Excessive Dietary Phosphorus Intake on Bone Health.Current osteoporosis reports · 2017Review
- Vitamin D, a modulator of musculoskeletal health in chronic kidney disease.Journal of cachexia, sarcopenia and muscle · 2017Review
- Osteoporosis in Frail Patients: A Consensus Paper of the Belgian Bone Club.Calcified tissue international · 2017Review
- Biochemical markers of mineral bone disorder in South African patients on maintenance haemodialysis.African health sciences · 2017Article
- Serum irisin levels correlated to peritoneal dialysis adequacy in nondiabetic peritoneal dialysis patients.PloS one · 2017Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Chronic kidney disease-mineral and bone disorder (CKD-MBD) is the term used to describe a constellation of biochemical abnormalities, bone disturbances that may lead to fractures, and extraskeletal calcification in soft tissues and arteries seen in CKD. This review focuses on the noninvasive diagnosis of renal osteodystrophy, the term used exclusively to define the bone pathology associated with CKD. Transiliac bone biopsy and histomorphometry with double-labeled tetracycline or its derivatives remains the gold standard for diagnosis of renal osteodystrophy. However, histomorphometry provides a 'window' into bone only at a single point in time, and is not clinically practical for studying continuous changes in bone morphology. Furthermore, the etiology of fractures in CKD is multifactorial and not fully explained by histomorphometry findings alone. The propensity of a bone to fracture is determined by bone strength, which is affected by bone mass and bone quality; the latter is a term used to describe the structure and composition of bone. Bone quantity is traditionally assessed by dual X-ray absorptiometry (DXA) and CT-based methods. Bone quality is more difficult to assess noninvasively, but newer techniques are emerging and are described in this review. Ultimately, the optimal diagnostic strategy for renal osteodystrophy may be a combination of multiple imaging techniques and biomarkers that are specific to each gender and race in CKD, with a goal of predicting fracture risk and optimizing therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.