Evidence map›Paper›PMID 23802087›Full record

ArticleOncoimmunology2013

Analysis of NKp30/NCR3 isoforms in untreated HIV-1-infected patients from the ANRS SEROCO cohort.

Nicole Prada, Guillemette Antoni, Frédéric Commo, Sylvie Rusakiewicz, Michaela Semeraro, Faroudy Boufassa, Olivier Lambotte, Laurence Meyer, Marie-Lise Gougeon, Laurence Zitvogel

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. A New Hope for CD56Frontiers in cellular and infection microbiology · 2020
    Article
  3. Article
  4. Review
  5. Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1.Journal of immunology (Baltimore, Md. : 1950) · 2018
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Nicole PradaINSERM U1015; Institut Gustave Roussy; Villejuif, France ; Institut Pasteur; Antiviral Immunity, Biotherapy and Vaccine Unit; Infection and Epidemiology Department; Paris, France.
Guillemette Antoni
Frédéric Commo
Sylvie Rusakiewicz
Michaela Semeraro
Faroudy Boufassa
Olivier Lambotte
Laurence Meyer
Marie-Lise Gougeon
Laurence Zitvogel
Institut Gustave Roussy · FRBicêtre Hospital · FRBiology of Infection · FRCentre de recherche en Epidémiologie et Santé des Populations · FRCentre d'Immunologie et des Maladies Infectieuses · FRImmunityBio (United States) · USInserm · FRUnited States Public Health Service · USUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells play a prominent role at the intersection between innate and cognate immunity, thus influencing the development of multiple pathological conditions including HIV-1-induced AIDS. Not only NK cells directly kill HIV-1-infected cells, but also control the maturation and/or elimination of dendritic cells (DCs). These functions are regulated by the delicate balance between activating and inhibiting receptors expressed at the NK-cell surface. Among the former, NKp30 has raised significant interest since the alternative splicing of its intracellular domain leads to differential effector functions, dictating the prognosis of patients bearing gastrointestinal sarcoma, and B7-H6 has recently been identified as its main ligand. Since NKp30 is downregulated in CD56

Indexed as

HIV-1immunosurveillancenatural course of infectionNKNKp30 isoforms

Identifiers

PMID23802087
PMCPMC3661172
OpenAlexW2092063434

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.