Evidence map›Paper›PMID 23802078›Full record

ArticleOncoimmunology2013

A new strategy to target regulatory T cells in solid tumors.

Audrey Thomas-Schoemann, Frédéric Batteux, Jérôme Alexandre

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Audrey Thomas-SchoemannUniversité Paris Descartes ; Unité de Formation et de Recherche des Sciences Pharmaceutiques et Biologiques; Paris, France ; Université Paris Descartes; Sorbonne Paris Cité; Faculté de Médecine; Paris, France ; Unité Fonctionnelle de Pharmacocinétique et Pharmacochimie; Assistance Publique-Hôpitaux de Paris; Hôpital Cochin; Paris, France.
Frédéric Batteux
Jérôme Alexandre
Assistance Publique – Hôpitaux de Paris · FRDélégation Paris 5 · FRSorbonne Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The depletion of regulatory T cells (Tregs) is a promising therapeutic strategy to enhance antitumor immune responses. Our recent findings indicate that low doses of arsenic trioxide can delay tumor growth in murine models of colon and breast cancer by depleting Tregs through oxidative and nitrosative bursts.

Indexed as

arsenic trioxidebreast cancercolon cancernitrosative stressoxidative stressregulatory T cell

Identifiers

PMID23802078
PMCPMC3661163
OpenAlexW2033155079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.