Evidence map›Paper›PMID 23801867›Full record

Trial reportWorld journal of gastroenterology2013

Fast-track surgery could improve postoperative recovery in radical total gastrectomy patients.

Fan Feng, Gang Ji, Ji-Peng Li, Xiao-Hua Li, Hai Shi, Zheng-Wei Zhao, Guo-Sheng Wu, Xiao-Nan Liu, Qing-Chuan Zhao

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03257280 (Impact on the Hospital Stay, of an Early Oral Nutrition Protocol Applied to Gastric Cancer Patients After Total Gastrectomy), which is not on this map. Cited by 42 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 17 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03257280 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Impact on the Hospital Stay, of an Early Oral Nutrition Protocol Applied to Gastric Cancer Patients After Total Gastrectomy: A Prospective Randomized Control Trial (DOPGT_2015)

TypeinterventionalSponsorHospital Universitari de BellvitgeRan2017 to 2023Enrolled84ConditionsEarly Oral Nutrition After Total Gastrectomy, Gastric CancerArmsEarly oral nutrition
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 17 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
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  8. Enhanced recovery versus conventional care in gastric cancer surgery: a meta-analysis of randomized and non-randomized controlled trials.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019
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  13. Systematic review of enhanced recovery after gastro-oesophageal cancer surgery.Annals of the Royal College of Surgeons of England · 2015
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  18. Trial
  19. Protocol for enhanced recovery after surgery improves short-term outcomes for patients with gastric cancer: a randomized clinical trial.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2017
    Trial
  20. A phase II study of an enhanced recovery after surgery protocol in gastric cancer surgery.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2016
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fan FengDepartment of Digestive Surgery, Xijing Hospital of Digestive Diseases, the Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Gang Ji
Ji-Peng Li
Xiao-Hua Li
Hai Shi
Zheng-Wei Zhao
Guo-Sheng Wu
Xiao-Nan Liu
Qing-Chuan Zhao
Air Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the impact of fast-track surgery (FTS) on hospital stay, cost of hospitalization and complications after radical total gastrectomy.

methodsA randomized, controlled clinical trial was conducted from November 2011 to August 2012 in the Department of Digestive Surgery, Xijing Hospital of Digestive Diseases, the Fourth Military Medical University. A total of 122 gastric cancer patients who met the selection criteria were randomized into FTS and conventional care groups on the first day of hospitalization. All patients received elective standard D2 total gastrectomy. Clinical outcomes, including duration of flatus and defecation, white blood cell count, postoperative pain, duration of postoperative stay, cost of hospitalization and complications were recorded and evaluated. Two specially trained doctors who were blinded to the treatment were in charge of evaluating postoperative outcomes, discharge and follow-up.

resultsA total of 119 patients finished the study, including 60 patients in the conventional care group and 59 patients in the FTS group. Two patients were excluded from the FTS group due to withdrawal of consent. One patient was excluded from the conventional care group because of a non-resectable tumor. Compared with the conventional group, FTS shortened the duration of flatus (79.03 ± 20.26 h vs 60.97 ± 24.40 h, P = 0.000) and duration of defecation (93.03 ± 27.95 h vs 68.00 ± 25.42 h, P = 0.000), accelerated the decrease in white blood cell count [P < 0.05 on postoperative day (POD) 3 and 4], alleviated pain in patients after surgery (P < 0.05 on POD 1, 2 and 3), reduced complications (P < 0.05), shortened the duration of postoperative stay (7.10 ± 2.13 d vs 5.68 ± 1.22 d, P = 0.000), reduced the cost of hospitalization (43783.25 ± 8102.36 RMB vs 39597.62 ± 7529.98 RMB, P = 0.005), and promoted recovery of patients.

conclusionFTS could be safely applied in radical total gastrectomy to accelerate clinical recovery of gastric cancer patients.

Indexed as

AgedChinaChi-Square DistributionCost SavingsDefecationFemaleGastrectomyHospital CostsHumansLength of StayMaleMiddle AgedMolecular Sequence DataPatient ReadmissionPostoperative ComplicationsProspective StudiesFast-track surgeryGastric cancerOutcomesPerioperative careRadical total gastrectomy

Identifiers

PMID23801867
PMCPMC3691044
OpenAlexW2106586953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.