Evidence map›Paper›PMID 23801655›Full record

ArticleMolecular nutrition & food research2013

Microbial characterization of probiotics--advisory report of the Working Group "8651 Probiotics" of the Belgian Superior Health Council (SHC).

Geert Huys, Nadine Botteldoorn, Frank Delvigne, Luc De Vuyst, Marc Heyndrickx, Bruno Pot, Jean-Jacques Dubois, Georges Daube

Abstract readConsensus Statement
In one paragraph

Article in Molecular nutrition & food research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Nigerian foods of probiotics relevance and chronic metal exposure: a systematic review.Environmental science and pollution research international · 2020
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Microbiology spectrum · 2026
    Article
  7. Article
  8. Review
  9. Frontiers in cellular and infection microbiology · 2026
    Article
  10. The interplay between probiotics and mast cells in gut inflammation: a mini-review.Frontiers in cellular and infection microbiology · 2026
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Evaluation ofMicroorganisms · 2023
    Article
  17. Article
  18. Article
  19. Current research in food science · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Geert HuysLaboratory for Microbiology & BCCM/LMG Bacteria Collection, Faculty of Sciences, Ghent University, Ghent, Belgium. geert.huys@ugent.be
Nadine Botteldoorn
Frank Delvigne
Luc De Vuyst
Marc Heyndrickx
Bruno Pot
Jean-Jacques Dubois
Georges Daube

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When ingested in sufficient numbers, probiotics are expected to confer one or more proven health benefits on the consumer. Theoretically, the effectiveness of a probiotic food product is the sum of its microbial quality and its functional potential. Whereas the latter may vary much with the body (target) site, delivery mode, human target population, and health benefit envisaged microbial assessment of the probiotic product quality is more straightforward. The range of stakeholders that need to be informed on probiotic quality assessments is extremely broad, including academics, food and biotherapeutic industries, healthcare professionals, competent authorities, consumers, and professional press. In view of the rapidly expanding knowledge on this subject, the Belgian Superior Health Council installed Working Group "8651 Probiotics" to review the state of knowledge regarding the methodologies that make it possible to characterize strains and products with purported probiotic activity. This advisory report covers three main steps in the microbial quality assessment process, i.e. (i) correct species identification and strain-specific typing of bacterial and yeast strains used in probiotic applications, (ii) safety assessment of probiotic strains used for human consumption, and (iii) quality of the final probiotic product in terms of its microbial composition, concentration, stability, authenticity, and labeling.

Indexed as

Food MicrobiologyAnimalsBacterial Typing TechniquesBifidobacteriumFood ContaminationFood LabelingHazard Analysis and Critical Control PointsHumansMolecular TypingPlatelet AggregationProbioticsQuality ControlVirulenceYeastsIdentificationLactic acid bacteriaProbioticsProduct quality controlSafety

Identifiers

PMID23801655
PMCPMC3910143

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.