Evidence map›Paper›PMID 23800864›Full record

ArticleNature genetics2013

Leveraging the species barrier to advance cancer therapy.

Song Zhao, Peter S Nelson

Abstract readNewsComment
PubMed Publisher
In one paragraph

Article in Nature genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Song Zhao
Peter S Nelson

Funding

The Co-Clinical Trial ProjectU01CA141457 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI PANDOLFI, PIER PAOLO · 2009 to 2013
$3.1M
NCI NIH HHS U01 CA141457
6 · The paper itself

Abstract

The discovery of new therapeutic targets and the personalization of treatments are two active areas of cancer research. New studies suggest that a 'co-clinical' approach may expedite both therapeutic target validation and risk stratification in patients with advanced prostate cancer.

Indexed as

Genes, Tumor SuppressorTherapies, InvestigationalAndrogen AntagonistsAndrogensAnimalsCellular SenescenceDNA-Binding ProteinsFemaleHumansMaleProstatic NeoplasmsSOX9 Transcription FactorTranscription FactorsAndrogen AntagonistsAndrogensDNA-Binding ProteinsSOX9 protein, humanSOX9 Transcription FactorTranscription FactorsZBTB7A protein, human

Identifiers

PMID23800864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.