Evidence map›Paper›PMID 23800483›Full record

Trial reportJournal of the American Academy of Child and Adolescent Psychiatry2013

Examination of disruptive behavior outcomes and moderation in a randomized psychotherapy trial for mood disorders.

Khrista Boylan, Heather A Macpherson, Mary A Fristad

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Academy of Child and Adolescent Psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00050557 (Family Psychoeducation), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00050557 phase1completednot on this map

Family Psychoeducation: Efficacy in Child Mood Disorders

TypeinterventionalSponsorMary FristadRan2001 to 2006Enrolled165ConditionsMood DisordersArmsMultifamily Psychoeducation Group (MFPG), Treatment as usual (TAU)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Treatment moderators of child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2015
    Trial
  4. Predictors and moderators in the randomized trial of multifamily psychoeducational psychotherapy for childhood mood disorders.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2014
    Trial
  5. Review
  6. Article
  7. Review
  8. Article
  9. Evidence-based psychosocial treatments for child and adolescent bipolar spectrum disorders.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Khrista BoylanDepartment of Psychiatry and Behavioral Neuroscience, McMaster University, Hamilton, ON, Canada. boylank@mcmaster.ca
Heather A Macpherson
Mary A Fristad
The Ohio State University · USMcMaster University · CA

Funding

FAMILY PSYCHOEDUCATION: EFFICACY IN CHILD MOOD DISORDERSR01MH061512 · NIMH · OHIO STATE UNIVERSITY · PI FRISTAD, MARY A · 2001 to 2005
$1.7M
NIMH NIH HHS R01 MH061512
6 · The paper itself

Abstract

objectiveMultifamily psychoeducational psychotherapy (MF-PEP) is an efficacious treatment for children with mood disorders. Given the comorbidity between disruptive behaviors and mood disorders, this study examined associations between disruptive behaviors and impairment, impact of MF-PEP on disruptive behaviors, and whether disruptive behaviors affected treatment response of mood symptoms.

methodSecondary analyses examined a randomized controlled trial of MF-PEP versus waitlist control (N = 165 children 8-11 years old with mood disorders and their parents). Comorbid behavioral diagnoses occurred in 97% of children. All participants continued treatment as usual.

resultsGreater degree of disruptive behaviors was associated with worse mood symptoms and impairment. Between-group analyses examining outcome of disruptive behaviors were nonsignificant. Within-group analyses and between-group effect sizes suggested that MF-PEP was associated with decreases in attention-deficit/hyperactivity disorder (d = 0.39), oppositional defiant disorder (d = 0.30), and overall disruptive behavior symptoms (d = 0.30), but not conduct disorder symptoms. Baseline severity of disruptive behaviors did not affect treatment response of mood symptoms to MF-PEP.

conclusionsMF-PEP is an effective intervention for children with mood disorders and provides some benefit for disruptive behaviors. Given that disruptive behavior severity does not affect children's ability to experience improved mood symptoms, MF-PEP may be an important early intervention for children with comorbid mood and disruptive behavior disorders. Subsequent intervention targeting behavioral symptoms after improvement in mood may be beneficial. Studies examining treatment sequencing for children with comorbid mood and disruptive behavior disorders are needed. Clinical trial registration information-Family psychoeducation for children with mood disorders; http://clinicaltrials.gov; NCT00050557.

Indexed as

Attention Deficit and Disruptive Behavior DisordersChildFamily TherapyFemaleHumansMaleMood DisordersSeverity of Illness IndexTreatment Outcome

Identifiers

PMID23800483
PMCPMC4326010
OpenAlexW1988063700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.