Evidence map›Paper›PMID 23800431›Full record

SynthesisSchizophrenia bulletin2014

Parental communication and psychosis: a meta-analysis.

Paulo de Sousa, Filippo Varese, William Sellwood, Richard P Bentall

Abstract readMeta-Analysis
In one paragraph

Synthesis in Schizophrenia bulletin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Psychosis in children of separated parents: A systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2020
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The clinical characterization of the patient with primary psychosis aimed at personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021
    Article
  12. Article
  13. What causes psychosis? An umbrella review of risk and protective factors.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018
    Article
  14. Childhood adversity and psychosis: generalised or specific effects?Epidemiology and psychiatric sciences · 2016
    Article
  15. Childhood adversities and psychosis: evidence, challenges, implications.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2016
    Article
  16. Article
  17. Review
  18. Evidence-based psychotherapy for the prevention and treatment of first-episode psychosis.European archives of psychiatry and clinical neuroscience · 2014
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paulo de SousaInstitute of Psychology, Health and Society, University of Liverpool, Liverpool, UK; sousa@liv.ac.uk.
Filippo VareseDivision of Clinical Psychology, School of Psychological Sciences, University of Manchester, Manchester, UK.
William SellwoodInstitute of Psychology, Health and Society, University of Liverpool, Liverpool, UK;
Richard P BentallInstitute of Psychology, Health and Society, University of Liverpool, Liverpool, UK;

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParental communication deviance (CD) has long been suggested as a potential risk factor for the development of psychosis and thought disorder in genetically sensitive offspring. However, the findings of the studies on the prevalence of CD in parents of psychotic patients have never been submitted to quantitative synthesis.

methodPsycINFO was searched from January 1959 to January 2012 for studies on the prevalence of CD in parents of psychotic patients. This search was supplemented with the results from a much larger systematic search (PsycINFO, PubMed, EMBASE, and Web of Science) on childhood trauma and psychosis.

resultsA total of 20 retrieved studies (n = 1753 parents) yielded a pooled g of large magnitude (0.97; 95% CI [0.76; 1.18]) with a significant amount of heterogeneity (Q = 33.63; P = .014; I (2) = 46.47). Subgroup and sensitivity analysis of methodological features (study's design, comparison group, diagnostic criteria, CD rating method, inter-rater reliability not reported, year of publication, and verbosity) and demographic characteristics (level of education or offspring's age) revealed that pooled effect size was stable and unlikely to have been affected by these features.

conclusionCD is highly prevalent in parents of psychotic offspring. This is discussed in the broader context of adoption and longitudinal studies that have reported a G × E interaction in the development of psychosis and thought disorder. A potential developmental mechanism is suggested to explain how CD may affect the developing offspring. The importance of further studies on CD and its potential value as a clinical concept are discussed.

Indexed as

Gene-Environment InteractionParent-Child RelationsCommunication DisordersHumansParentsPsychotic DisordersRisk Factorscommunication deviancefamilypsychosisthought disorder

Identifiers

PMID23800431
PMCPMC4059429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.