ReviewNutrition journal2013
The beneficial role of vitamin D in obesity: possible genetic and cell signaling mechanisms.
Review in Nutrition journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 74 citations in OpenAlex.
- Changes in Bone Turnover, Inflammatory, Oxidative Stress, and Metabolic Markers in Women Consuming Iron plus Vitamin D Supplements: a Randomized Clinical Trial.Biological trace element research · 2021Trial
- Effectiveness of vitamin D therapy in improving metabolomic biomarkers in obesity phenotypes: Two randomized clinical trials.International journal of obesity (2005) · 2018Trial
- Serum vitamin D and obesity among US adolescents, NHANES 2011-2018.Frontiers in pediatrics · 2024Article
- Understanding diabetes-induced cardiomyopathy from the perspective of renin angiotensin aldosterone system.Pflugers Archiv : European journal of physiology · 2022Review
- Differences in Fat-Free Mass According to Serum Vitamin D Level and Calcium Intake: Korea National Health and Nutrition Examination Survey 2008-2011.Journal of clinical medicine · 2021Article
- Association of serum 25-hydroxyvitamin D with metabolic syndrome and type 2 diabetes: a one sample Mendelian randomization study.BMC geriatrics · 2021Article
- Molecular mechanisms of vitamin D plus Bisphenol A effects on adipogenesis in human adipose-derived mesenchymal stem cells.Diabetology & metabolic syndrome · 2021Article
- Vitamin D Status and Its Correlation With Anthropometric and Biochemical Indicators of Cardiometabolic Risk in Serbian Underground Coal Miners in 2016.Frontiers in nutrition · 2021Article
- Vitamin D status and cardiovascular outcome.Journal of endocrinological investigation · 2019Review
- Gender Differences in Vitamin D Status in China.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Effects of dietary vitamin levels on physiological responses, blood profiles, and reproductive performance in gestating sows.Journal of animal science and technology · 2019Article
- Vitamin D receptor gene polymorphisms are associated with triceps skin fold thickness and body fat percentage but not with body mass index or waist circumference in Han Chinese.Lipids in health and disease · 2019Article
- Association of Vitamin D Status with Chronic Disease Risk Factors and Cognitive Dysfunction in 50⁻70 Year Old Adults.Nutrients · 2019Article
- Role of pregnancy and obesity on vitamin D status, transport, and metabolism in baboons.American journal of physiology. Endocrinology and metabolism · 2019Article
- Vitamin D Receptor Gene Haplotype and Late-Onset Obesity in Iranian Azeri Turkish Women.Maedica · 2017Article
- Vitamin D, sub-inflammation and insulin resistance. A window on a potential role for the interaction between bone and glucose metabolism.Reviews in endocrine & metabolic disorders · 2017Review
- Low vitamin D status and obesity: Role of nutritionist.Reviews in endocrine & metabolic disorders · 2017Review
- Article
- Short-term UVB irradiation significantly increases vitamin D serum concentration in obese patients: a clinical pilot study.Endocrine · 2017Article
- Vitamin D deficiency and related risk factors in patients with diabetic nephropathy.The Journal of international medical research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence rates of overweight and obesity are considered an important public issue in the United States, and both of these conditions are increasing among both children and adults. There is evidence of aberrations in the vitamin D-endocrine system in obese subjects. Vitamin D deficiency is highly prevalent in patients with obesity, and many studies have demonstrated the significant effect of calcitriol on adipocytes. Genetic studies have provided an opportunity to determine which proteins link vitamin D to obesity pathology, including the vitamin D receptor, toll-like receptors, the renin-angiotensin system, apolipoprotein E, vascular endothelial growth factor, and poly (ADP-ribose) polymerase-1. Vitamin D also exerts its effect on obesity through cell-signaling mechanisms, including matrix metalloproteinases, mitogen-activated protein kinase pathways, the reduced form of nicotinamide adenine dinucleotide phosphate, prostaglandins, reactive oxygen species, and nitric oxide synthase.In conclusion, vitamin D may have a role in obesity. The best form of vitamin D for use in the obese individuals is calcitriol because it is the active form of the vitamin D₃ metabolite, its receptors are present in adipocytes, and modulates inflammatory cytokine expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.