ArticleGenome biology2013
Phytophthora capsici-tomato interaction features dramatic shifts in gene expression associated with a hemi-biotrophic lifestyle.
Article in Genome biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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68 citing papers in PubMed, 150 citations in OpenAlex.
- Pathogen-triggered m⁶A epitranscriptomic reprogramming is linked to host defense responses in the Piper nigrum-Phytophthora capsici pathosystem.Plant cell reports · 2026Article
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- A Phase-Separated SR Protein Reprograms Host Pre-mRNA Splicing to Enhance Disease Susceptibility.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A conserved fungal effector disturbs CaNature communications · 2025Article
- An RXLR effector disrupts vesicle trafficking at ER-Golgi interface for Phytophthora capsici pathogenicity.Molecules and cells · 2024Article
- Dual transcriptional characterization of spinach and Peronospora effusa during resistant and susceptible race-cultivar interactions.BMC genomics · 2024Article
- Morphological and Molecular Identification ofPlants (Basel, Switzerland) · 2024Article
- The Phytophthora parasitica effector AVH195 interacts with ATG8, attenuates host autophagy, and promotes biotrophic infection.BMC biology · 2024Article
- The Dynamic Interaction between Oil Palm andJournal of fungi (Basel, Switzerland) · 2024Article
- Dual transcriptomic analysis reveals early inducedFrontiers in plant science · 2024Article
- Functional genomics identifies a small secreted protein that plays a role during the biotrophic to necrotrophic shift in the root rot pathogenFrontiers in plant science · 2024Article
- The effectors of Phytophthora infestans impact host immunity upon regulation of antagonistic hormonal activities.Planta · 2023Article
- Polygenic pathogen networks influence transcriptional plasticity in the Arabidopsis-Botrytis pathosystem.Genetics · 2023Article
- Unraveling Plant Cell Death duringMicroorganisms · 2022Review
- Review
- Chickpea Roots Undergoing Colonisation byMicroorganisms · 2022Article
- Strive or thrive: Trends inFrontiers in plant science · 2022Article
- Draft genome assemblies for tree pathogens Phytophthora pseudosyringae and Phytophthora boehmeriae.G3 (Bethesda, Md.) · 2021Article
- Haustorium formation and a distinct biotrophic transcriptome characterize infection of Nicotiana benthamiana by the tree pathogen Phytophthora kernoviae.Molecular plant pathology · 2021Article
- Metabolomic Evaluation of Tissue-Specific Defense Responses in Tomato Plants Modulated by PGPR-Priming againstPlants (Basel, Switzerland) · 2021Article
8 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPlant-microbe interactions feature complex signal interplay between pathogens and their hosts. Phytophthora species comprise a destructive group of fungus-like plant pathogens, collectively affecting a wide range of plants important to agriculture and natural ecosystems. Despite the availability of genome sequences of both hosts and microbes, little is known about the signal interplay between them during infection. In particular, accurate descriptions of coordinate relationships between host and microbe transcriptional programs are lacking.
resultsHere, we explore the molecular interaction between the hemi-biotrophic broad host range pathogen Phytophthora capsici and tomato. Infection assays and use of a composite microarray allowed us to unveil distinct changes in both P. capsici and tomato transcriptomes, associated with biotrophy and the subsequent switch to necrotrophy. These included two distinct transcriptional changes associated with early infection and the biotrophy to necrotrophy transition that may contribute to infection and completion of the P. capsici lifecycle
conclusionsOur results suggest dynamic but highly regulated transcriptional programming in both host and pathogen that underpin P. capsici disease and hemi-biotrophy. Dynamic expression changes of both effector-coding genes and host factors involved in immunity, suggests modulation of host immune signaling by both host and pathogen. With new unprecedented detail on transcriptional reprogramming, we can now explore the coordinate relationships that drive host-microbe interactions and the basic processes that underpin pathogen lifestyles. Deliberate alteration of lifestyle-associated transcriptional changes may allow prevention or perhaps disruption of hemi-biotrophic disease cycles and limit damage caused by epidemics.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.