Evidence map›Paper›PMID 23799875›Full record

ArticleActa psychiatrica Scandinavica2014

Measuring psychotic depression.

S D Østergaard, B S Meyers, A J Flint, B H Mulsant, E M Whyte, C M Ulbricht, P Bech, A J Rothschild, STOP-PD Study Group

Abstract read
In one paragraph

Article in Acta psychiatrica Scandinavica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Vigour in active avoidance.Scientific reports · 2017
    Article
  12. Article
  13. Gender Differences in the Clinical Characteristics of Psychotic Depression: Results from the CRESCEND Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2015
    Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

S D ØstergaardUnit for Psychiatric Research, Aalborg Psychiatric Hospital, Aalborg University hospital, Aalborg, Denmark; Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
B S Meyers
A J Flint
B H Mulsant
E M Whyte
C M Ulbricht
P Bech
A J Rothschild
STOP-PD Study Group

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024996 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2007 to 2011
$49.6M
Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
WITHIN SUBJ VARIABILITY IN MEASUREMENTS DRUG METABOL ENZYMES IN HLTY SUBJM01RR000056 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEVINE, ARTHUR S · 1985 to 2006
$29.2M
Cornell ACISR for Late Life DepressionP30MH068638 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2003 to 2007
$6.5M
Acute Pharmacotherapy of Psychotic DepressionU01MH062518 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2002 to 2015
$5.0M
Acute Pharmacotherapy of Unipolar Psychotic DepressionU01MH062565 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WHYTE, ELLEN M · 2002 to 2015
$3.0M
Acute Pharmacotherapy of Unipolar Psychotic DepressionU01MH062624 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ROTHSCHILD, ANTHONY J · 2002 to 2015
$2.9M
Acute Pharmacotherapy of Unipolar Psychotic DepressionU01MH062446 · NIMH · UNIVERSITY HEALTH NETWORK · PI FLINT, ALASTAIR J. · 2002 to 2015
$2.0M
Intervention to Prevent Post-Stroke Major DepressionK23MH067710 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WHYTE, ELLEN M · 2004 to 2008
$857k
Complex Trials for Severe Geriatric Mood DisordersK24MH069430 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MULSANT, BENOIT H · 2004 to 2008
$601k
NCATS NIH HHS UL1 TR000005NCATS NIH HHS UL1 TR000457NCRR NIH HHS M01 RR000056NCRR NIH HHS M01-RR024153NCRR NIH HHS RR000056NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1 RR024996NCRR NIH HHS UL1RR024996NIMH NIH HHS K23 MH067710NIMH NIH HHS K24 MH069430NIMH NIH HHS MH067710NIMH NIH HHS MH069430NIMH NIH HHS MH 62446NIMH NIH HHS MH 62518NIMH NIH HHS MH 62565NIMH NIH HHS MH 62624NIMH NIH HHS P30 MH068368NIMH NIH HHS P30 MH068638NIMH NIH HHS U01 MH062446NIMH NIH HHS U01 MH062518NIMH NIH HHS U01 MH062565NIMH NIH HHS U01 MH062624
6 · The paper itself

Abstract

objectivePsychotic depression (PD) is a highly debilitating condition, which needs intensive monitoring. However, there is no established rating scale for evaluating the severity of PD. The aim of this analysis was to assess the psychometric properties of established depression rating scales and a number of new composite rating scales, covering both depressive and psychotic symptoms, in relation to PD.

methodThe psychometric properties of the rating scales were evaluated based on data from the Study of Pharmacotherapy of Psychotic Depression.

resultsA rating scale consisting of the 6-item Hamilton melancholia subscale (HAM-D6 ) plus five items from the Brief Psychiatric Rating Scale (BPRS), named the HAMD-BPRS11 , displayed clinical validity (Spearman's correlation coefficient between HAMD-BPRS11 and Clinical Global Impression - Severity (CGI-S) scores = 0.79-0.84), responsiveness (Spearman's correlation coefficient between change in HAMD-BPRS11 and Clinical Global Impression - Improvement (CGI-I) scores = -0.74--0.78) and unidimensionality (Loevinger's coefficient of homogeneity = 0.41) in the evaluation of PD. The HAM-D6 fulfilled the same criteria, whereas the full 17-item Hamilton Depression Scale failed to meet criteria for unidimensionality.

conclusionOur results suggest that the HAMD-BPRS11 is a more valid measure than pure depression scales for evaluating the severity of PD.

Indexed as

AdultAffective Disorders, PsychoticBrief Psychiatric Rating ScaleDepressive DisorderFemaleHumansMaleMiddle AgedPrincipal Component AnalysisPsychiatric Status Rating ScalesPsychometricsRandomized Controlled Trials as TopicReproducibility of ResultsSeverity of Illness Indexaffective disordersdepressionpsychometricspsychoses

Identifiers

PMID23799875
PMCPMC3819398

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.