Evidence map›Paper›PMID 23798996›Full record

ArticlePloS one2013

Aspergillus felis sp. nov., an emerging agent of invasive aspergillosis in humans, cats, and dogs.

Vanessa R Barrs, Tineke M van Doorn, Jos Houbraken, Sarah E Kidd, Patricia Martin, Maria Dolores Pinheiro, Malcolm Richardson, Janos Varga, Robert A Samson

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Vanessa R BarrsFaculty of Veterinary Science, The University of Sydney, New South Wales, Australia. vanessa.barrs@sydney.edu.au
Tineke M van Doorn
Jos Houbraken
Sarah E Kidd
Patricia Martin
Maria Dolores Pinheiro
Malcolm Richardson
Janos Varga
Robert A Samson
Royal Netherlands Academy of Arts and Sciences · NLUniversity of Sydney · AUHospital de São João · PTManchester Academic Health Science Centre · GBUniversity of Szeged · HUWomen's and Children's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a novel heterothallic species in Aspergillus section Fumigati, namely A. felis (neosartorya-morph) isolated from three host species with invasive aspergillosis including a human patient with chronic invasive pulmonary aspergillosis, domestic cats with invasive fungal rhinosinusitis and a dog with disseminated invasive aspergillosis. Disease in all host species was often refractory to aggressive antifungal therapeutic regimens. Four other human isolates previously reported as A. viridinutans were identified as A. felis on comparative sequence analysis of the partial β-tubulin and/or calmodulin genes. A. felis is a heterothallic mold with a fully functioning reproductive cycle, as confirmed by mating-type analysis, induction of teleomorphs within 7 to 10 days in vitro and ascospore germination. Phenotypic analyses show that A. felis can be distinguished from the related species A. viridinutans by its ability to grow at 45°C and from A. fumigatus by its inability to grow at 50°C. Itraconazole and voriconazole cross-resistance was common in vitro.

Indexed as

Air MicrobiologyAnimalsAntifungal AgentsAspergillosisAspergillusCaspofunginCat DiseasesCatsCommunicable Diseases, EmergingDog DiseasesDogsDrug Resistance, FungalEchinocandinsFluconazoleGenes, FungalHumansAntifungal AgentsCaspofunginEchinocandinsFluconazoleLipopeptides

Identifiers

PMID23798996
PMCPMC3683053
OpenAlexW2117185974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.