ArticleThe Journal of cell biology2013
Replication and trafficking of a plant virus are coupled at the entrances of plasmodesmata.
Article in The Journal of cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
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Who cites it
86 citing papers in PubMed, 165 citations in OpenAlex.
- Global Genetic Diversity, Provisional Strain Demarcation, and Evolutionary Dynamics of Potato Virus X (PVX).Viruses · 2026Article
- Viral vector-based imaging uncovers infection-induced re-localization of pepino mosaic virus proteins.Journal of virology · 2026Article
- Pepino Mosaic Virus: A Globally Important Tomato Pathogen and a Rising Model in Molecular Virology.Molecular plant pathology · 2026Review
- Pepino Mosaic Virus in Tomato: Challenges, Control Strategies, and Future Prospects for Resistance Breeding.International journal of molecular sciences · 2025Review
- Article
- Illuminating viral replication in living plants: A conditional probe system for tracking replicase dynamics.Plant physiology · 2025Article
- Live-cell imaging of a plant virus replicase during infection using a genetically encoded, antibody-based probe.Plant physiology · 2025Article
- Alphaflexiviridae in Focus: Genomic Signatures, Conserved Elements and Viral-Driven Cellular Remodeling.Viruses · 2025Review
- Live-cell RNA imaging with the inactivated endonuclease Csy4 enables new insights into plant virus transport through plasmodesmata.PLoS pathogens · 2025Article
- Protein P5 of pear chlorotic leaf spot-associated virus is a pathogenic factor that suppresses RNA silencing and enhances virus movement.Molecular plant pathology · 2024Article
- AtHVA22a, a plant-specific homologue of Reep/DP1/Yop1 family proteins is involved in turnip mosaic virus propagation.Molecular plant pathology · 2024Article
- Mechanisms of plant virus cell-to-cell transport: new lessons from complementation studies.Frontiers in plant science · 2024Article
- Fine Structure of Plasmodesmata-Associated Membrane Bodies Formed by Viral Movement Protein.Plants (Basel, Switzerland) · 2023Article
- Article
- Properties of Plant Virus Protein Encoded by the 5'-Proximal Gene of Tetra-Cistron Movement Block.International journal of molecular sciences · 2023Article
- Three-dimensional analysis of membrane structures associated with tomato spotted wilt virus infection.Plant, cell & environment · 2023Article
- A sword or a buffet: plant endomembrane system in viral infections.Frontiers in plant science · 2023Review
- Interaction between Movement Proteins ofViruses · 2022Article
- Reticulons 3 and 6 interact with viral movement proteins.Molecular plant pathology · 2022Article
- Transcriptome analyses unveiled differential regulation of AGO and DCL genes by pepino mosaic virus strains.Molecular plant pathology · 2022Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Plant viruses use movement proteins (MPs) to modify intercellular pores called plasmodesmata (PD) to cross the plant cell wall. Many viruses encode a conserved set of three MPs, known as the triple gene block (TGB), typified by Potato virus X (PVX). In this paper, using live-cell imaging of viral RNA (vRNA) and virus-encoded proteins, we show that the TGB proteins have distinct functions during movement. TGB2 and TGB3 established endoplasmic reticulum-derived membranous caps at PD orifices. These caps harbored the PVX replicase and nonencapsidated vRNA and represented PD-anchored viral replication sites. TGB1 mediated insertion of the viral coat protein into PD, probably by its interaction with the 5' end of nascent virions, and was recruited to PD by the TGB2/3 complex. We propose a new model of plant virus movement, which we term coreplicational insertion, in which MPs function to compartmentalize replication complexes at PD for localized RNA synthesis and directional trafficking of the virus between cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.