ArticleProceedings of the National Academy of Sciences of the United States of America2013
Genome of a SAR116 bacteriophage shows the prevalence of this phage type in the oceans.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.
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92 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Assessing the Risks of Potential Pathogens and Antibiotic Resistance Genes Among Heterogeneous Habitats in a Temperate Estuary Wetland: a Meta-analysis.Microbial ecology · 2025Pooled it
- Regional environmental heterogeneity under contrasting anthropogenic pressures has differential effects on particle-attached than free-living bacteria communities in coral reef waters.Microbiology spectrum · 2026Article
- Ribonucleotide reductases recapitulate biogeographic patterns within virioplankton according to ocean biogeochemistry.bioRxiv : the preprint server for biology · 2026Article
- Marine Autographiviridae phages exhibit high genetic diversity and global-scale biogeographic patterns.Communications biology · 2025Article
- Marine Bacteriophages as Next-Generation Therapeutics: Insights into Antimicrobial Potential and Application.Viruses · 2025Review
- Isolation, complete characterization and phylogeography of the first bacteriophage againstMicrobial genomics · 2025Article
- Review
- Culture-supported ecophysiology of the SAR116 clade demonstrates metabolic and spatial niche partitioning.The ISME journal · 2025Article
- A novel virus potentially evolved from the N4-like viruses represents a unique viral family:Applied and environmental microbiology · 2024Article
- Effect of Light Regime onJournal of microbiology and biotechnology · 2024Article
- A novel flavobacterial phage abundant during green tide, representing a new viral family,Applied and environmental microbiology · 2024Article
- Long-read powered viral metagenomics in the oligotrophic Sargasso Sea.Nature communications · 2024Article
- Effects of Light and Dark Conditions on the Transcriptome of Aging Cultures of Candidatus Puniceispirillum marinum IMCC1322.Journal of microbiology (Seoul, Korea) · 2024Article
- Genome sequences of the firstMicrobial genomics · 2024Article
- The structure and assembly mechanisms of T4-like cyanophages community in the South China Sea.Microbiology spectrum · 2024Article
- Genomic diversity and biogeographic distributions of a novel lineage of bacteriophages that infect marine OM43 bacteria.Microbiology spectrum · 2023Article
- Genomic Analysis and Taxonomic Characterization of Seven Bacteriophage Genomes Metagenomic-Assembled from the Dishui Lake.Viruses · 2023Article
- Article
- Newly identified HMO-2011-type phages reveal genomic diversity and biogeographic distributions of this marine viral group.The ISME journal · 2022Article
- An InducibleViruses · 2022Article
32 more citing papers are in PubMed but not listed here.
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The abundance, genetic diversity, and crucial ecological and evolutionary roles of marine phages have prompted a large number of metagenomic studies. However, obtaining a thorough understanding of marine phages has been hampered by the low number of phage isolates infecting major bacterial groups other than cyanophages and pelagiphages. Therefore, there is an urgent requirement for the isolation of phages that infect abundant marine bacterial groups. In this study, we isolated and characterized HMO-2011, a phage infecting a bacterium of the SAR116 clade, one of the most abundant marine bacterial lineages. HMO-2011, which infects "Candidatus Puniceispirillum marinum" strain IMCC1322, has an ~55-kb dsDNA genome that harbors many genes with novel features rarely found in cultured organisms, including genes encoding a DNA polymerase with a partial DnaJ central domain and an atypical methanesulfonate monooxygenase. Furthermore, homologs of nearly all HMO-2011 genes were predominantly found in marine metagenomes rather than cultured organisms, suggesting the novelty of HMO-2011 and the prevalence of this phage type in the oceans. A significant number of the viral metagenome sequences obtained from the ocean surface were best assigned to the HMO-2011 genome. The number of reads assigned to HMO-2011 accounted for 10.3%-25.3% of the total reads assigned to viruses in seven viromes from the Pacific and Indian Oceans, making the HMO-2011 genome the most or second-most frequently assigned viral genome. Given its ability to infect the abundant SAR116 clade and its widespread distribution, Puniceispirillum phage HMO-2011 could be an important resource for marine virus research.
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