ArticleBrain structure & function2014
A direct anterior cingulate pathway to the primate primary olfactory cortex may control attention to olfaction.
Article in Brain structure & function, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Effect of ketamine intervention on hemodynamic responses in patients with treatment-resistant depression.Scientific reports · 2026Article
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- AAV9-mediated transduction of memory circuits following convection-enhanced delivery into the olfactory bulbs.Gene therapy · 2025Article
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- The effect of the apolipoprotein E ε4 allele and olfactory function on odor identification networks.Brain and behavior · 2024Article
- Semantic context-dependent neural representations of odors in the human piriform cortex revealed by 7T MRI.Human brain mapping · 2024Article
- The brain functional connectivity alterations in traumatic patients with olfactory disorder after low-level laser therapy demonstrated by fMRI.The neuroradiology journal · 2023Article
- Aberrant olfactory network functional connectivity in people with olfactory dysfunction following COVID-19 infection: an exploratory, observational study.EClinicalMedicine · 2023Article
- Article
- Pathways for Contextual Memory: The Primate Hippocampal Pathway to Anterior Cingulate Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Odors Associated With Autobiographical Memory Induce Visual Imagination of Emotional Scenes as Well as Orbitofrontal-Fusiform Activation.Frontiers in neuroscience · 2021Article
- Cortical Connections Position Primate Area 25 as a Keystone for Interoception, Emotion, and Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Anterior Cingulate Pathways May Affect Emotions Through Orbitofrontal Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Mirror trends of plasticity and stability indicators in primate prefrontal cortex.The European journal of neuroscience · 2017Article
- Posterior Orbitofrontal and Anterior Cingulate Pathways to the Amygdala Target Inhibitory and Excitatory Systems with Opposite Functions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Area 4 has layer IV in adult primates.The European journal of neuroscience · 2014Review
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2 authors.
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Abstract
Behavioral and functional studies in humans suggest that attention plays a key role in activating the primary olfactory cortex through an unknown circuit mechanism. We report that a novel pathway from the anterior cingulate cortex, an area which has a key role in attention, projects directly to the primary olfactory cortex in rhesus monkeys, innervating mostly the anterior olfactory nucleus. Axons from the anterior cingulate cortex formed synapses mostly with spines of putative excitatory pyramidal neurons and with a small proportion of a neurochemical class of inhibitory neurons that are thought to have disinhibitory effect on excitatory neurons. This novel pathway from the anterior cingulate is poised to exert a powerful excitatory effect on the anterior olfactory nucleus, which is a critical hub for odorant processing via extensive bilateral connections with primary olfactory cortices and the olfactory bulb. Acting on the anterior olfactory nucleus, the anterior cingulate may activate the entire primary olfactory cortex to mediate the process of rapid attention to olfactory stimuli.
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