ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2013
Deficits in physical function among young childhood cancer survivors.
Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 11 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
71 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Skeletal muscle health in childhood cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Parents' perceptions of physical activity for their children with cancer: a qualitative meta-synthesis.Frontiers in pediatrics · 2025Pooled it
- Physical function patient-reported outcomes among adolescent and young adult cancer survivors: A systematic review.Cancer medicine · 2024Pooled it
- Effect of concurrent training on physical performance and quality of life in children with malignancy: A systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Physical and functional performance assessment in pediatric oncology: a systematic review.Pediatric research · 2022Pooled it
- Adventure therapy for child, adolescent, and young adult cancer patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- Physical activity and fitness among pediatric cancer survivors: a meta-analysis of observational studies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Pooled it
- Short and long-term impairments of cardiopulmonary fitness level in previous childhood cancer cases: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Pooled it
- Systematic review and meta-analysis of objective and subjective quality of life among pediatric, adolescent, and young adult bone tumor survivors.Pediatric blood & cancer · 2015Pooled it
- Recommendations for cardiomyopathy surveillance for survivors of childhood cancer: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group.The Lancet. Oncology · 2015Guideline
- Clinical practice guideline and expert consensus recommendations for rehabilitation among children with cancer: A systematic review.CA: a cancer journal for cliniciansPooled it
- Remotely delivered resistance training program in adult sarcoma survivors: a pilot study.BMC cancer · 2026Trial
- Late outcomes of adult survivors of childhood non-Hodgkin lymphoma: A report from the St. Jude Lifetime Cohort Study.Pediatric blood & cancer · 2017Trial
- State Laws Supporting Adapted Physical Education Access and Quality for Students With Disabilities.The Journal of school health · 2026Article
- Physical activity behaviors and screen time in young childhood cancer survivors: the Physical Activity in Childhood Cancer Survivors Study.Journal of cancer survivorship : research and practice · 2026Article
- Associations between perceived cancer impact and measures of health behavior in survivors of childhood cancer.Journal of cancer survivorship : research and practice · 2026Article
- Barriers to Occupational and Physical Therapy Utilization for Children With Cancer.Cancer medicine · 2026Article
- Associations between Cardiopulmonary Fitness and Cardiovascular Events in Survivors of Childhood Cancer: A Report from the St. Jude Lifetime Cohort.Medicine and science in sports and exercise · 2025Article
- Reduced aerobic capacity in children with multisystem inflammatory syndrome in children (MIS-C) after PICU admission: a retrospective cohort study, 2020-2022.BMC pediatrics · 2025Article
- Physical impairments, activity limitations, and participation restrictions of childhood acute lymphoblastic leukemia survivors with and without hip osteonecrosis: a PETALE cohort study.Journal of cancer survivorship : research and practice · 2025Observational
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeChildhood cancer survivors (CCSs) are at risk for physical disability. The aim of this investigation was to characterize and compare physical performance among CCSs and a group of siblings age < 18 years and determine if diagnosis, treatment, and physical activity levels were associated with lower performance scores.
methodsCCSs ≥ 5 years from diagnosis and a sibling comparison group were recruited and evaluated for strength, mobility, and fitness. Physical performance measures were compared in regression models between survivors and siblings by diagnosis and among survivors by treatment exposures and physical activity levels.
resultsCCSs (n = 183; mean age ± standard deviation [SD], 13.5 ± 2.5 years; 53% male) scored lower than siblings (n = 147; mean age ± SD, 13.4 ± 2.4 years; 50% male) on lower-extremity strength testing, the timed up-and-go (TUG) test, and the 6-minute walk (6MW) test, despite reporting similar levels and types of habitual physical activity. The lowest scores were prevalent among survivors of CNS tumors and bone and soft tissue sarcomas on strength testing (score ± SD: CNS tumors, 76.5 ± 4.7; sarcoma 67.1 ± 7.2 v siblings, 87.3 ± 2.4 Newton-meters quadricep strength at 90° per second; P = .04 and .01, respectively) and among CNS tumor survivors on the TUG (score ± SD: 5.1 ± 0.1 v siblings, 4.4 ± 0.1 seconds; P < .001) and 6MW tests (score ± SD: 533.3 ± 15.6 v siblings, 594.1 ± 8.3 m; P < .001).
conclusionCCSs may have underlying physiologic deficits that interfere with function that cannot be completely overcome by participation in regular physical activity. These survivors may need referral for specialized exercise interventions in addition to usual counseling to remain physically active.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.