Evidence map›Paper›PMID 23796926›Full record

ArticleAntimicrobial agents and chemotherapy2013

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens.

Philana Ling Lin, Teresa Coleman, Jonathan P J Carney, Brian J Lopresti, Jaime Tomko, Dan Fillmore, Veronique Dartois, Charles Scanga, L James Frye, Christopher Janssen and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 186 citations in OpenAlex.

  1. Trial
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  3. bioRxiv : the preprint server for biology · 2026
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  17. GEODE: anFrontiers in pharmacology · 2025
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68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Philana Ling LinDepartment of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Teresa ColemanDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Jonathan P J CarneyDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Brian J LoprestiDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Jaime TomkoDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Dan FillmoreDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Veronique DartoisDepartment of Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.
Charles ScangaDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
L James FryeCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Christopher JanssenDivision of Laboratory Animal Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Edwin KleinDivision of Laboratory Animal Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Clifton E BarryTuberculosis Research Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
JoAnne L FlynnDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA joanne@pitt.edu.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · USNational Institutes of Health · USUniversity Hospital, Newark · US

Funding

Development Of New Chemotherapeutics For TuberculosisZIAAI000693 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BARRY, CLIFTON · 2009 to 2025
$20.1M
Experimental Animal Models of TB: Chemotherapeutics and ImagingZIAAI000734 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BARRY, CLIFTON · 2009 to 2025
$19.6M
Defining how the spectrum of latency affects reactivation of TBR01HL106804 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FLYNN, JOANNE L., KIRSCHNER, DENISE E · 2010 to 2013
$2.6M
A multi-scale model to predict outcomes of immunomodulation and drug therapy duriR01EB012579 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FLYNN, JOANNE L., KIRSCHNER, DENISE E · 2011 to 2014
$2.3M
Intramural NIH HHS ZIA AI000693NHLBI NIH HHS R01 HL106804
6 · The paper itself

Abstract

Trials to test new drugs currently in development against tuberculosis in humans are impractical. All animal models to prioritize new regimens are imperfect, but nonhuman primates (NHPs) infected with

Identifiers

PMID23796926
PMCPMC3754323
OpenAlexW2140708650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.