Evidence map›Paper›PMID 23796920›Full record

ArticleAntimicrobial agents and chemotherapy2013

Restrictive Streptomycin Resistance Mutations Decrease the Formation of Attaching and Effacing Lesions in Escherichia coli O157:H7 Strains.

Chun Chen, Carla A Blumentritt, Meredith M Curtis, Vanessa Sperandio, Alfredo G Torres, Edward G Dudley

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pathogenic and non-pathogenicDisease models & mechanisms · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chun ChenDepartment of Food Science, the Penn State University, University Park, Pennsylvania, USA.
Carla A BlumentrittDepartments of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Meredith M CurtisDepartments of Microbiology and Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Vanessa SperandioDepartments of Microbiology and Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Alfredo G TorresDepartments of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Edward G DudleyDepartment of Food Science, the Penn State University, University Park, Pennsylvania, USA egd100@psu.edu.
Pennsylvania State University · USThe University of Texas Medical Branch at Galveston · USThe University of Texas Southwestern Medical Center · US

Funding

Quorum sensing regulation of EHEC virulence genesR01AI053067 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SPERANDIO, VANESSA · 2003 to 2017
$6.3M
NIAID NIH HHS R01 AI053067
6 · The paper itself

Abstract

Streptomycin binds to the bacterial ribosome and disrupts protein synthesis by promoting misreading of mRNA. Restrictive mutations on the ribosomal subunit protein S12 confer a streptomycin resistance (Str

Identifiers

PMID23796920
PMCPMC3754346
OpenAlexW2141938814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.