ArticleAmerican journal of ophthalmology2013
Risk of choroidal neovascularization among the uveitides.
Article in American journal of ophthalmology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.
- Diagnostic accuracy of optical coherence tomography angiography for choroidal neovascularization: a systematic review and meta-analysis.BMC ophthalmology · 2019Pooled it
- Optical coherence tomography angiography features of inflammatory choroidal neovascularizaton in Vogt-Koyanagi-Harada disease.Indian journal of ophthalmology · 2026Article
- Twelve-month functional and structural outcomes ofFrontiers in cellular and infection microbiology · 2026Article
- Pediatric peripapillary choroidal neovascularization secondary to ocular sarcoidosis: a long-term follow-up case.BMC ophthalmology · 2025Article
- Preclinical Retinal Disease Models: Applications in Drug Development and Translational Research.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Diagnostic Challenges in Inflammatory Choroidal Neovascularization.Medicina (Kaunas, Lithuania) · 2024Review
- Presence of Choroidal Caverns in Patients with Posterior and Panuveitis.Biomedicines · 2023Article
- ROLE OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN DETECTING AND MONITORING INFLAMMATORY CHOROIDAL NEOVASCULARIZATION.Retina (Philadelphia, Pa.) · 2022Article
- Simultaneous bilateral inflammatory choroidal neovascularization in a case of healed serpiginous-like choroiditis.GMS ophthalmology cases · 2022Article
- Immune Cells in Subretinal Wound Healing and Fibrosis.Frontiers in cellular neuroscience · 2022Review
- Subfoveal retinal pigment epithelium inflammatory lesion presenting as a sign of reactivation of tubercular multifocal choroiditis.BMJ case reports · 2021Article
- Clinical course of choroidal neovascular membrane in West Nile virus chorioretinitis: a case report.Journal of medical case reports · 2021Article
- Inflammatory Choroidal Neovascular Membranes: Clinical Profile, Treatment Effectiveness, and Visual Prognosis.Journal of ophthalmology · 2021Article
- Retrobulbar triamcinolone for inflammatory choroidal neovascularization in pregnancy.BMC ophthalmology · 2020Article
- Inflammatory Choroidal Neovascular Membranes in Patients With Noninfectious Uveitis: The Place of Intravitreal Anti-VEGF Therapy.Medical hypothesis, discovery & innovation ophthalmology journal · 2020Review
- Favorable clinical outcome with intravitreal aflibercept treatment in a case with bilateral choroidal neovascular membrane and quiescent Vogt-Koyanagi-Harada syndrome.GMS ophthalmology cases · 2020Article
- Optical coherence tomography angiography in uveitis.Journal of ophthalmic inflammation and infection · 2019Review
- Optical Coherence Tomography Angiography in Eyes with Non-infectious Posterior Uveitis; Some Practical Aspects.Medical hypothesis, discovery & innovation ophthalmology journal · 2019Review
- An update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management.Journal of ophthalmic inflammation and infection · 2018Review
- Intravitreal Aflibercept as an Adjunct to Systemic Therapy in a Case of Choroidal Neovascular Membrane Associated with Sympathetic Ophthalmia.Turkish journal of ophthalmology · 2018Article
Corrections and comments
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Authors and funding
12 authors at 10 institutions in 1 country.
Funding
Abstract
purposeTo evaluate the risk, risk factors, and visual impact of choroidal neovascularization (CNV) in uveitis cases.
designRetrospective cohort study.
methodsStandardized medical record review at 5 tertiary centers.
resultsAmong 15,137 uveitic eyes (8868 patients), CNV was rare in the cases of anterior or intermediate uveitis. Among the 4041 eyes (2307 patients) with posterior uveitis or panuveitis, 81 (2.0%) had CNV at presentation. Risk factors included posterior uveitis in general and specific uveitis syndromes affecting the outer retina-retinal pigment epithelium-choroid interface. Among the 2364 eyes (1357 patients) with posterior uveitis or panuveitis and free of CNV at the time of cohort entry, the cumulative 2-year incidence of CNV was 2.7% (95% confidence interval [CI], 1.8% to 3.5%). Risk factors for incident CNV included currently active inflammation (adjusted hazard ratio [aHR], 2.13; 95% CI, 1.26 to 3.60), preretinal neovascularization (aHR, 3.19; 95% CI, 1.30 to 7.80), and prior diagnosis of CNV in the contralateral eye (aHR, 5.79; 95% CI, 2.77 to 12.09). Among specific syndromes, the incidence was greater in Vogt-Koyanagi-Harada syndrome (aHR, 3.37; 95% CI, 1.52 to 7.46) and punctate inner choroiditis (aHR, 8.67; 95% CI, 2.83 to 26.54). Incident CNV was associated with a 2-line loss of visual acuity (+0.19 logarithm of the minimal angle of resolution units; 95% CI, 0.079 to 0.29) from the preceding visit.
conclusionsCNV is an uncommon complication of uveitis associated with visual impairment that occurs more commonly in forms affecting the outer retina-retinal pigment epithelium-choroid interface, during periods of inflammatory activity, in association with preretinal neovascularization, and in second eyes of patients with unilateral CNV. Because CNV is treatable, a systematic approach to early detection in high-risk patients may be appropriate.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.