ArticleThe American journal on addictions
Impact of cannabis use during stabilization on methadone maintenance treatment.
Article in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Cannabinoid exposure across substance use disorders: Short-term symptom benefits without sustained therapeutic gains in a tier-weighted systematic review.European psychiatry : the journal of the Association of European Psychiatrists · 2026Pooled it
- Alleviation of opioid withdrawal by cannabis and delta-9-tetrahydrocannabinol: A systematic review of observational and experimental human studies.Drug and alcohol dependence · 2022Pooled it
- The effects of dronabinol during detoxification and the initiation of treatment with extended release naltrexone.Drug and alcohol dependence · 2015Trial
- No evidence for reduction of opioid-withdrawal symptoms by cannabis smoking during a methadone dose taper.The American journal on addictions · 2015Trial
- Marijuana use and achievement of abstinence from alcohol and other drugs among people with substance dependence: a prospective cohort study.Drug and alcohol dependence · 2014Trial
- Clinicians' Perspectives on Cannabis Use and Cannabis Treatment in Clients Undertaking Opioid Dependence Treatment.Drug and alcohol review · 2025Article
- Cannabis Use in Opioid Maintenance Therapy: Prevalence, Clinical Correlates and Reasons for Use.Brain sciences · 2025Article
- Impact of Co-Occurring Psychiatric Comorbidities and Substance Use Disorders on Outcomes in Adolescents and Young Adults with Opioid Use Disorder: A Retrospective Cohort Study.Pharmaceuticals (Basel, Switzerland) · 2025Article
- "Smoking weed it gets you over the hump": Cannabis co-use as a facilitator of decreased opioid use among people who inject drugs in Los Angeles, California.Drug and alcohol dependence reports · 2024Article
- Perspectives regarding cannabis use: Results from a qualitative study of individuals engaged in substance use treatment in Georgia and Connecticut.Drug and alcohol dependence reports · 2024Article
- Cannabis donation as a harm reduction strategy: a case study.Harm reduction journal · 2024Article
- The Impact of Longitudinal Substance Use Patterns on the Risk of Opioid Agonist Therapy Discontinuation: A Repeated Measures Latent Class Analysis.International journal of mental health and addiction · 2024Article
- Implications of Cannabis Legalization on Substance-Related Benefits and Harms for People Who Use Opioids: A Canadian Perspective.Cannabis and cannabinoid research · 2023Article
- The Cannabis-Dependent Relationship Between Methadone Treatment Dose and Illicit Opioid Use in a Community-Based Cohort of People Who Use Drugs.Cannabis and cannabinoid research · 2023Article
- Cannabinoids-Perspectives for Individual Treatment in Selected Patients: Analysis of the Case Series.Biomedicines · 2022Article
- The impact of marijuana use on cocaine use outcomes among patients in methadone maintenance treatment across five trials of contingency management.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022Article
- The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya.Substance abuse treatment, prevention, and policy · 2022Article
- Prevalence of Cannabis Use and Cannabis Route of Administration among Massachusetts Adults in Buprenorphine Treatment for Opioid Use Disorder.Substance use & misuse · 2022Article
- Green Hope: Perspectives on Cannabis from People who Use Opioids.Sociological inquiry · 2021Article
- Cannabis use in patients treated for opioid use disorder pre- and post-recreational cannabis legalization in Canada.Substance abuse treatment, prevention, and policy · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesIllicit drug use, particularly of cannabis, is common among opiate-dependent individuals and has the potential to impact treatment in a negative manner.
methodsTo examine this, patterns of cannabis use prior to and during methadone maintenance treatment (MMT) were examined to assess possible cannabis-related effects on MMT, particularly during methadone stabilization. Retrospective chart analysis was used to examine outpatient records of patients undergoing MMT (n = 91), focusing specifically on past and present cannabis use and its association with opiate abstinence, methadone dose stabilization, and treatment compliance.
resultsObjective rates of cannabis use were high during methadone induction, dropping significantly following dose stabilization. History of cannabis use correlated with cannabis use during MMT but did not negatively impact the methadone induction process. Pilot data also suggested that objective ratings of opiate withdrawal decrease in MMT patients using cannabis during stabilization. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: The present findings may point to novel interventions to be employed during treatment for opiate dependence that specifically target cannabinoid-opioid system interactions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.