Evidence map›Paper›PMID 23795823›Full record

Trial reportJournal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 532014

Predictors and moderators in the randomized trial of multifamily psychoeducational psychotherapy for childhood mood disorders.

Heather A MacPherson, Guillermo Perez Algorta, Amy N Mendenhall, Benjamin W Fields, Mary A Fristad

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Treatment moderators of child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2015
    Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Parenting Stress Among Caregivers of Children With Bipolar Spectrum Disorders.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2018
    Article
  8. Review
  9. Article
  10. Evidence-based psychosocial treatments for child and adolescent bipolar spectrum disorders.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2014
    Review
  11. Future directions for research on youth with bipolar spectrum disorders.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Heather A MacPhersona Departments of Psychiatry and Psychology , The Ohio State University.
Guillermo Perez Algorta
Amy N Mendenhall
Benjamin W Fields
Mary A Fristad
The Ohio State University · USNationwide Children's Hospital · USUniversity of Kansas · US

Funding

The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
FAMILY PSYCHOEDUCATION: EFFICACY IN CHILD MOOD DISORDERSR01MH061512 · NIMH · OHIO STATE UNIVERSITY · PI FRISTAD, MARY A · 2001 to 2005
$1.7M
NCATS NIH HHS UL1 TR001070NIMH NIH HHS R01 MH061512
6 · The paper itself

Abstract

This study investigated predictors and moderators of mood symptoms in the randomized controlled trial (RCT) of Multi-Family Psychoeducational Psychotherapy (MF-PEP) for childhood mood disorders. Based on predictors and moderators in RCTs of psychosocial interventions for adolescent mood disorders, we hypothesized that children's greater functional impairment would predict worse outcome, whereas children's stress/trauma history and parental expressed emotion and psychopathology would moderate outcome. Exploratory analyses examined other demographic, functioning, and diagnostic variables. Logistic regression and linear mixed effects modeling were used in this secondary analysis of the MF-PEP RCT of 165 children, ages 8 to 12, with mood disorders, a majority of whom were male (73%) and White, non-Hispanic (90%). Treatment nonresponse was significantly associated with higher baseline levels of global functioning (i.e., less impairment; Cohen's d = 0.51) and lower levels of stress/trauma history (d = 0.56) in children and Cluster B personality disorder symptoms in parents (d = 0.49). Regarding moderators, children with moderately impaired functioning who received MF-PEP had significantly decreased mood symptoms (t = 2.10, d = 0.33) compared with waitlist control. MF-PEP had the strongest effect on severely impaired children (t = 3.03, d = 0.47). Comprehensive assessment of demographic, youth, parent, and familial variables should precede intervention. Treatment of mood disorders in high-functioning youth without stress/trauma histories and with parents with elevated Cluster B symptoms may require extra therapeutic effort, whereas severely impaired children may benefit most from MF-PEP.

Indexed as

AdolescentAdultChildFamily TherapyFemaleHealth EducationHumansLogistic ModelsMaleMiddle AgedMood DisordersParentsPsychiatric Status Rating ScalesPsychotherapy, GroupRisk FactorsTreatment Outcome

Identifiers

PMID23795823
PMCPMC3797211
OpenAlexW2012298739

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.