Evidence map›Paper›PMID 23795707›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2014

Distress and the parenting dynamic among BRCA1/2 tested mothers and their partners.

Darren Mays, Tiffani A DeMarco, George Luta, Beth N Peshkin, Andrea F Patenaude, Katherine A Schneider, Judy E Garber, Kenneth P Tercyak

Open access · greenAbstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Family Adjustment to Hereditary Cancer Syndromes: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Darren MaysCancer Prevention & Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center.
Tiffani A DeMarcoCancer Prevention & Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center.
George LutaDepartment of Biostatistics, Bioinformatics, and Biomathematics, Cancer Prevention & Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center.
Beth N PeshkinCancer Prevention & Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center.
Andrea F PatenaudeDepartment of Psychosocial Oncology & Palliative Care, Dana-Farber Cancer Institute.
Katherine A SchneiderCenter for Cancer Genetics & Prevention, Dana-Farber Cancer Institute.
Judy E GarberCenter for Cancer Genetics & Prevention, Dana-Farber Cancer Institute.
Kenneth P TercyakCancer Prevention & Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center.
Georgetown University · USDana-Farber Cancer Institute · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI STEPHEN W BYERS · 1990 to 2026
$71.5M
Parent Communication of BRCA1/2 Test Results to ChildrenR01HG002686 · NHGRI · GEORGETOWN UNIVERSITY · PI TERCYAK, KENNETH · 2003 to 2009
$3.1M
NCI NIH HHS P30 CA051008NCI NIH HHS P30CA051008NHGRI NIH HHS R01 HG002686
6 · The paper itself

Abstract

objectiveTo investigate the influence of dyadic parenting relationships on psychological distress among mothers tested for BRCA1/2 genetic mutations and their untested partners.

methodsData were from a prospective study of mothers suspected to be at risk for hereditary breast/ovarian cancer who underwent genetic counseling and BRCA1/2 testing and their untested parenting partners (n = 109 parenting dyads). Participants completed assessments before and 1 month after genetic testing. Structural equation modeling was used to examine relationships among mothers' and partners' psychological distress, decisional conflict surrounding communication of test results to their offspring, and the parent-child communication relationship. Psychological distress was measured using items modified from the Brief Symptom Inventory.

resultsAmong mothers, greater psychological distress (B = 0.29, p < .001) and poorer parent-child communication (B = -0.12, p < .01) at baseline predicted greater distress at follow-up. Among partners, greater distress at baseline predicted greater distress at follow-up (B = 0.67, p < .001). Mother and partner decisional conflict at baseline were equally associated with the other dyad member's distress at follow-up (B = 1.17, p < .01), but not their own distress.

conclusionsOur findings indicate that conflicted decision-making over family communication of hereditary breast/ovarian cancer genetic test results for one member of a parenting dyad adversely affects the other dyad member's psychological well-being. Interventions to improve outcomes for mothers who may be at-risk for hereditary breast and ovarian cancer and undergoing BRCA1/2 genetic testing should attend to mothers' and their partners' preferences regarding family communication about hereditary cancer risk.

Indexed as

Genes, BRCA1Genes, BRCA2Parent-Child RelationsStress, PsychologicalAdolescentAdultBreast NeoplasmsChildCommunicationConflict, PsychologicalDecision MakingFemaleGenetic CounselingGenetic Predisposition to DiseaseGenetic TestingHumans

Identifiers

PMID23795707
PMCPMC3883806
OpenAlexW2324640697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.