Evidence map›Paper›PMID 23795583›Full record

ReviewJournal of neuroendocrinology2013

Nuclear receptor coactivators: regulators of steroid action in brain and behaviour.

M J Tetel, K D Acharya

Open access · greenAbstract readReview
In one paragraph

Review in Journal of neuroendocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

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  13. TLDc proteins: new players in the oxidative stress response and neurological disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2017
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

M J TetelNeuroscience Program, Wellesley College, Wellesley, MA, USA.
K D Acharya
Wellesley College · US

Funding

Mechanisms of Steroid Hormone Action in BrainR01DK061935 · NIDDK · WELLESLEY COLLEGE · PI TETEL, MARC JEFFREY · 2002 to 2014
$2.7M
NIDDK NIH HHS R01 DK061935NIDDK NIH HHS R01 DK61935
6 · The paper itself

Abstract

Steroid hormones act in specific regions of the brain to alter behaviour and physiology. Although it has been well established that the bioavailability of the steroid and the expression of its receptor is critical for understanding steroid action in the brain, the importance of nuclear receptor coactivators in the brain is becoming more apparent. The present review focuses on the function of the p160 family of coactivators, which includes steroid receptor coactivator-1 (SRC-1), SRC-2 and SRC-3, in steroid receptor action in the brain. The expression, regulation and function of these coactivators in steroid-dependent gene expression in both brain and behaviour are discussed.

Indexed as

AnimalsBrainGene Expression RegulationHormonesNuclear Receptor CoactivatorsReceptors, SteroidSexual Behavior, AnimalHormonesNuclear Receptor CoactivatorsReceptors, Steroidandrogen receptorhypothalamusoestrogen receptorprogestin receptorsex behaviourSRC-2 (GRIP1/TIF2/NCoA-2)steroid hormonessteroid receptor coactivator-1 (SRC-1/NcoA-1)

Identifiers

PMID23795583
PMCPMC3830605
OpenAlexW2068116428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.