Evidence map›Paper›PMID 23795343›Full record

ArticleRecent patents on biomedical engineering2013

Design and Application of Magnetic-based Theranostic Nanoparticle Systems.

Aniket S Wadajkar, Jyothi U Menon, Tejaswi Kadapure, Richard T Tran, Jian Yang, Kytai T Nguyen

Abstract read
In one paragraph

Article in Recent patents on biomedical engineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Co-encapsulating CoFeIET nanobiotechnology · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Nanopharmacology in translational hematology and oncology.International journal of nanomedicine · 2014
    Review
  16. Article
  17. Assessing the barriers to image-guided drug delivery.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aniket S WadajkarDepartment of Bioengineering, The University of Texas at Arlington, Arlington, TX 76019 ; Joint Biomedical Engineering Program between The University of Texas at Arlington and The University of Texas Southwestern Medical Center, Dallas, TX 75390.
Jyothi U Menon
Tejaswi Kadapure
Richard T Tran
Jian Yang
Kytai T Nguyen

Funding

Creating Safe Biodegradable Photoluminescent Implant PolymersR01EB012575 · NIBIB · UNIVERSITY OF TEXAS ARLINGTON · PI YANG, JIAN · 2011 to 2014
$1.2M
Enabling aliphatic biodegradable photoluminescent polymeric biomaterialsR21EB009795 · NIBIB · UNIVERSITY OF TEXAS ARLINGTON · PI YANG, JIAN · 2009 to 2010
$404k
NIBIB NIH HHS R01 EB012575NIBIB NIH HHS R21 EB009795
6 · The paper itself

Abstract

Recently, magnetic-based theranostic nanoparticle (MBTN) systems have been studied, researched, and applied extensively to detect and treat various diseases including cancer. Theranostic nanoparticles are advantageous in that the diagnosis and treatment of a disease can be performed in a single setting using combinational strategies of targeting, imaging, and/or therapy. Of these theranostic strategies, magnetic-based systems containing magnetic nanoparticles (MNPs) have gained popularity because of their unique ability to be used in magnetic resonance imaging, magnetic targeting, hyperthermia, and controlled drug release. To increase their effectiveness, MNPs have been decorated with a wide variety of materials to improve their biocompatibility, carry therapeutic payloads, encapsulate/bind imaging agents, and provide functional groups for conjugation of biomolecules that provide receptor-mediated targeting of the disease. This review summarizes recent patents involving various polymer coatings, imaging agents, therapeutic agents, targeting mechanisms, and applications along with the major requirements and challenges faced in using MBTN for disease management.

Indexed as

hyperthermiaimaging agentsmagnetic nanoparticlespolymeric shelltheranosticstherapeutic agents

Identifiers

PMID23795343
PMCPMC3686518

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.