Evidence map›Paper›PMID 23795222›Full record

ArticleEuropean journal of integrative medicine2013

Advances in Integrative Nanomedicine for Improving Infectious Disease Treatment in Public Health.

Iris R Bell, Gary E Schwartz, Nancy N Boyer, Mary Koithan, Audrey J Brooks

Open access · greenAbstract read
In one paragraph

Article in European journal of integrative medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Biomimetic cell membrane-coated poly(lactic-Bioengineering & translational medicine · 2023
    Review
  5. Review
  6. Recent developments of nanotherapeutics for targeted and long-acting, combination HIV chemotherapy.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2019
    Review
  7. Nanomedicine applications in women's health: state of the art.International journal of nanomedicine · 2018
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Iris R BellDepartment of Family and Community Medicine, the University of Arizona College of Medicine, Tucson, AZ, USA ; Department of Psychiatry, the University of Arizona College of Medicine, Tucson, AZ, USA ; Department of Psychology, the University of Arizona, Tucson, AZ, USA ; College of Nursing, the University of Arizona, Tucson, AZ, USA ; Department of Medicine (Integrative Medicine), the University of Arizona College of Medicine, Tucson, AZ, USA ; Mel and Enid Zuckerman College of Public Health, the University of Arizona, Tucson, AZ USA.
Gary E Schwartz
Nancy N Boyer
Mary Koithan
Audrey J Brooks
University of Arizona · US

Funding

Arizona Complementary and Alternative Medicine Research Training ProgramT32AT001287 · NCCIH · UNIVERSITY OF ARIZONA · PI BELL, IRIS ROBERTA · 2002 to 2011
$3.2M
NCCIH NIH HHS T32 AT001287
6 · The paper itself

Abstract

introductionInfectious diseases present public health challenges worldwide. An emerging integrative approach to treating infectious diseases is using nanoparticle (NP) forms of traditional and alternative medicines. Advantages of nanomedicine delivery methods include better disease targeting, especially for intracellular pathogens, ability to cross membranes and enter cells, longer duration drug action, reduced side effects, and cost savings from lower doses.

methodsWe searched Pubmed articles in English with keywords related to nanoparticles and nanomedicine. Nanotechnology terms were also combined with keywords for drug delivery, infectious diseases, herbs, antioxidants, homeopathy, and adaptation.

resultsNPs are very small forms of material substances, measuring 1-100 nanometers along at least one dimension. Compared with bulk forms, NPs' large ratio of surface-area-to-volume confers increased reactivity and adsorptive capacity, with unique electromagnetic, chemical, biological, and quantum properties. Nanotechnology uses natural botanical agents for green manufacturing of less toxic NPs. DISCUSSION: Nanoparticle herbs and nutriceuticals can treat infections via improved bioavailability and antiinflammatory, antioxidant, and immunomodulatory effects. Recent studies demonstrate that homeopathic medicines may contain source and/or silica nanoparticles because of their traditional manufacturing processes. Homeopathy, as a form of nanomedicine, has a promising history of treating epidemic infectious diseases, including malaria, leptospirosis and HIV/AIDS, in addition to acute upper respiratory infections. Adaptive changes in the host's complex networks underlie effects.

conclusionsNanomedicine is integrative, blending modern technology with natural products to reduce toxicity and support immune function. Nanomedicine using traditional agents from alternative systems of medicine can facilitate progress in integrative public health approaches to infectious diseases.

Indexed as

AdaptationAntioxidantsDrug delivery systemsHerbal medicineHomeopathyInfectious disease treatmentMedicinal plantsNanomedicineNanoparticlesNetwork medicineSilica

Identifiers

PMID23795222
PMCPMC3685499
OpenAlexW1967021767

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.