ArticlePersonalized medicine2012
Incorporating direct-to-consumer genomic information into patient care: attitudes and experiences of primary care physicians.
Article in Personalized medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 6 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Building capacity for genomics in primary care: a scoping review of practitioner attitudes, education needs, and enablers.Frontiers in medicine · 2025Pooled it
- Sharing behavior and health care utilization following direct-to-consumer genetic testing: a systematic review.Open research Europe · 2025Pooled it
- Direct-to-consumer genetic testing: an updated systematic review of healthcare professionals' knowledge and views, and ethical and legal concerns.European journal of human genetics : EJHG · 2022Pooled it
- General practitioners' (GPs) experience, attitudes and needs on clinical genetic services: a systematic review.Family medicine and community health · 2022Pooled it
- Delivering genomic medicine in the United Kingdom National Health Service: a systematic review and narrative synthesis.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Pooled it
- Internet-Based Direct-to-Consumer Genetic Testing: A Systematic Review.Journal of medical Internet research · 2015Pooled it
- Determining the effects and challenges of incorporating genetic testing into primary care management of hypertensive patients with African ancestry.Contemporary clinical trials · 2016Trial
- Multidisciplinary stakeholder-informed identification of key characteristics for implementation of workplace genetic testing.HGG advances · 2025Article
- Survey of Professionals of the European Public Health Association (EUPHA) towards Direct-to-Consumer Genetic Testing.European journal of public health · 2023Article
- Design and rationale of GUARDD-US: A pragmatic, randomized trial of genetic testing for APOL1 and pharmacogenomic predictors of antihypertensive efficacy in patients with hypertension.Contemporary clinical trials · 2022Article
- Considerations for developing regulations for direct-to-consumer genetic testing: a scoping review using the 3-I framework.Journal of community genetics · 2022Article
- May direct-to-consumer genetic testing have an impact on general practitioners' daily practice? a cross-sectional study of patients' intentions towards this approach.BMC family practice · 2021Article
- Knowledge, Attitudes, and Perceived Barriers toward Genetic Testing and Pharmacogenomics among Healthcare Workers in the United Arab Emirates: A Cross-Sectional Study.Journal of personalized medicine · 2020Article
- The implementation of pharmacogenomics into UK general practice: a qualitative study exploring barriers, challenges and opportunities.Journal of community genetics · 2020Article
- Health and kinship matter: Learning about direct-to-consumer genetic testing user experiences via online discussions.PloS one · 2020Article
- Primary Care Physicians' Knowledge, Attitudes, and Experience with Personal Genetic Testing.Journal of personalized medicine · 2019Article
- Informing Integration of Genomic Medicine Into Primary Care: An Assessment of Current Practice, Attitudes, and Desired Resources.Frontiers in genetics · 2019Article
- Communication of cancer-related genetic and genomic information: A landscape analysis of reviews.Translational behavioral medicine · 2018Review
- Prescriber Attitudes Toward Implementation of Pharmacogenomic Testing in a Family Medicine Residency Program.PRiMER (Leawood, Kan.) · 2018Article
- Clinical pharmacogenomics: patient perspectives of pharmacogenomic testing and the incidence of actionable test results in a chronic disease cohort.Personalized medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
aimDespite predictions of increased clinical applications, little is known about primary care providers' (PCPs') readiness to apply genomics to patient care. The aim was to assess PCPs' current experience with genetic testing, their assessment of the understandability and clinical utility of information in sample direct-to-consumer reports for genomic assessment of disease risk and warfarin dosing and attitudes toward genomic medicine. MATERIALS &
methodsA web-based survey of PCPs who are members of Knowledge Networks' Physician Consulting Network was conducted.
resultsOf the 502 respondents (23.3% response rate), most ordered genetic tests infrequently. When presented with the direct-to-consumer genomic testing reports, most believed the reports were understandable, and would be willing to review results with a patient, and many believed the results would be helpful in patient management.
conclusionDespite limited experience with genetic tests, PCPs are open to helping patients understand genomic information. However, additional physician education is needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.