ArticleInternational journal of medical sciences2013
Areca nut chewing and risk of atrial fibrillation in Taiwanese men: a nationwide ecological study.
Article in International journal of medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Association between atrial fibrillation and age-related macular degeneration: A nationwide cohort study.Eye (London, England) · 2025Article
- Betel Quid Use and Tuberculosis Transmission: A Neglected Focus Area for Tuberculosis Control in Low- and Middle-Income Countries.Open forum infectious diseases · 2024Review
- Oral anticoagulant decreases stroke recurrence in patients with atrial fibrillation detected after stroke.Frontiers in cardiovascular medicine · 2022Article
- Lower Risk of Dementia in Patients With Atrial Fibrillation Taking Non-Vitamin K Antagonist Oral Anticoagulants: A Nationwide Population-Based Cohort Study.Journal of the American Heart Association · 2021Article
- Risk of ischemic stroke in patients with end-stage renal disease receiving peritoneal dialysis with new-onset atrial fibrillation.Journal of the Chinese Medical Association : JCMA · 2020Article
- Betel-Quid Chewing, Heart Failure, and Premature Ventricular Contractions in Patients with Cardiopulmonary Symptoms.International journal of environmental research and public health · 2020Article
- Areca nut chewing is associated with common mental disorders: a population-based study.Social psychiatry and psychiatric epidemiology · 2018Article
- Areca Nut Chewing and the Risk of Re-hospitalization and Mortality Among Patients With Acute Coronary Syndrome in Pakistan.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2018Article
- Gypenosides induce cell death and alter gene expression in human oral cancer HSC-3 cells.Experimental and therapeutic medicine · 2017Article
- Hormone replacement therapy and risk of atrial fibrillation in Taiwanese menopause women: A nationwide cohort study.Scientific reports · 2016Article
- Areca Nut Chewing Complicated with Non-Obstructive and Obstructive ST Elevation Myocardial Infarction.Acta Cardiologica Sinica · 2016Article
- Prevalence and Spectrum of TBX5 Mutation in Patients with Lone Atrial Fibrillation.International journal of medical sciences · 2016Article
- Article
- Mutational spectrum of the NKX2-5 gene in patients with lone atrial fibrillation.International journal of medical sciences · 2014Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAreca nut chewing is associated with the risk of obesity, metabolic syndrome, hypertension, and cardiovascular mortality. Although a few case reports or case series have suggested the link between areca nut chewing and cardiac arrhythmias, information about the relationship between areca nut chewing and atrial fibrillation (AF) is lacking. Thus, a nationwide ecological study was conducted to investigate this.
methodsTwo national datasets, the nationwide population-based 2005 Taiwan National Health Insurance Research dataset (NHIRD) and the 2005 National Health Interview Survey (NHIS), were used for analyses. The clinical characteristics, inhabited area and medical histories for 375,360 eligible males were retrieved from the 2005 NHIRD. Health related behaviors including areca nut chewing, cigarette smoking, infrequent vegetable eating, and exercise habit were collected from the 2005 NHIS. The prevalence of AF and the areca nut chewing rate were evaluated by multivariate analysis.
resultsOf the 375,360 males (mean age, 44 years old), 1,326 (0.35%) were diagnosed with AF. The higher areca nut chewing rate, the higher prevalence rate of AF in Taiwan (Spearman correlation coefficient r=0.558, p=0.007). After adjusting for other covariates, the current areca nut chewing rate was found to be independently associated with the prevalence of AF. The adjusted odd ratio for areca nut chewing was 1.02 (95% CI=1.00-1.04) in risk of AF prevalence.
conclusionsAreca nut chewing is independently associated with the prevalence of AF in Taiwanese men. However, further exploration of the underlying mechanisms is necessary.
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