ArticleOrganic process research & development2013
Asymmetric Preparation of
Article in Organic process research & development, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Asymmetric biomimetic transamination of α-keto phosphonates enabled by chiral pyridoxamines and synergistic solvent.Nature communications · 2026Article
- A Quantum Mechanical Approach to The Mechanism of Asymmetric Synthesis of Chiral Amine by Imine Reductase from Stackebrandtia Nassauensis.ChemPlusChem · 2025Article
- An Extremely Sensitive Ultra-High Throughput Growth Selection Assay for the Identification of Amidase Activity.Applied microbiology and biotechnology · 2024Article
- Modeling the alkylation of amines with alkyl bromides: explaining the low selectivity due to multiple alkylation.Journal of molecular modeling · 2024Article
- A growth selection system for the directed evolution of amine-forming or converting enzymes.Nature communications · 2022Article
- Construction and yield optimization of a cinnamylamine biosynthesis route in Escherichia coli.Biotechnology for biofuels and bioproducts · 2022Article
- Stereo-Divergent Enzyme Cascades to Convert Racemic 4-Phenyl-2-Butanol into either (S)- or (R)-Corresponding Chiral Amine.Chembiochem : a European journal of chemical biology · 2022Article
- Direct Conversion of Hydrazones to Amines using Transaminases.ChemCatChem · 2021Article
- Identification, Characterization, and Site-Specific Mutagenesis of a Thermostable ω-Transaminase fromACS omega · 2021Article
- Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase fromMaterials (Basel, Switzerland) · 2021Article
- Enzymatic Kinetic Resolution by Addition of Oxygen.Angewandte Chemie (International ed. in English) · 2021Review
- Power of Biocatalysis for Organic Synthesis.ACS central science · 2021Review
- Biocatalysis: Enzymatic Synthesis for Industrial Applications.Angewandte Chemie (International ed. in English) · 2021Review
- Improving the Thermostability and Activity of Transaminase FromFrontiers in chemistry · 2021Article
- Multi-enzyme pyruvate removal system to enhance (RSC advances · 2020Article
- Genome mining and characterisation of a novel transaminase with remote stereoselectivity.Scientific reports · 2019Article
- Characterisation of a solvent-tolerant haloarchaeal (R)-selective transaminase isolated from a Triassic period salt mine.Applied microbiology and biotechnology · 2019Article
- The identification and use of robust transaminases from a domestic drain metagenome.Green chemistry : an international journal and green chemistry resource : GC · 2019Article
- A Practical Electrophilic Nitrogen Source for the Synthesis of Chiral Primary Amines by Copper-Catalyzed Hydroamination.Journal of the American Chemical Society · 2018Article
- Asymmetric Synthesis of (R)-1-Alkyl-Substituted Tetrahydro-ß-carbolines Catalyzed by Strictosidine Synthases.Angewandte Chemie (International ed. in English) · 2018Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This account focuses on the application of ω-transaminases, lyases, and oxidases for the preparation of amines considering mainly work from our own lab. Examples are given to access α-chiral primary amines from the corresponding ketones as well as terminal amines from primary alcohols via a two-step biocascade. 2,6-Disubstituted piperidines, as examples for secondary amines, are prepared by biocatalytical regioselective asymmetric monoamination of designated diketones followed by spontaneous ring closure and a subsequent diastereoselective reduction step. Optically pure
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.