Evidence map›Paper›PMID 23794749›Full record

ArticleJournal of computational physics2013

A multiscale MDCT image-based breathing lung model with time-varying regional ventilation.

Youbing Yin, Jiwoong Choi, Eric A Hoffman, Merryn H Tawhai, Ching-Long Lin

Abstract read
In one paragraph

Article in Journal of computational physics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Article
  3. Forward Computational Modeling of Respiratory Airflow.Applied sciences (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Computational fluid dynamics of the airways after left-upper pulmonary lobectomy: A case study.International journal for numerical methods in biomedical engineering · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Differences in Particle Deposition Between Members of Imaging-Based Asthma Clusters.Journal of aerosol medicine and pulmonary drug delivery · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. A review of inflammatory mechanism in airway diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Youbing YinDepartment of Mechanical and Industrial Engineering, The University of Iowa, Iowa City, IA 52242, US ; IIHR-Hydroscience and Engineering, The University of Iowa, Iowa City, IA 52242, US ; Department of Radiology, The University of Iowa, Iowa City, IA 52242, US.
Jiwoong Choi
Eric A Hoffman
Merryn H Tawhai
Ching-Long Lin

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
Image and Model Based Analysis of Lung DiseasesR01HL064368 · NHLBI · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 1999 to 2009
$15.6M
Multi-center Structural & Functional Quantitative CT Pulmonary PhenotypingR01HL112986 · NHLBI · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2012 to 2016
$4.6M
Multiscale Interaction of Pulmonary Gas Flow and Lung Tissue MechanicsR01HL094315 · NHLBI · UNIVERSITY OF IOWA · PI LIN, CHING-LONG · 2010 to 2013
$1.4M
Large-Scale Computing and Visualization for Cardiopulmonary ImagingS10RR022421 · NCRR · UNIVERSITY OF IOWA · PI LIN, CHING-LONG · 2008 to 2008
$474k
NCRR NIH HHS S10 RR022421NHLBI NIH HHS R01 HL064368NHLBI NIH HHS R01 HL094315NHLBI NIH HHS R01 HL112986NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

A novel algorithm is presented that links local structural variables (regional ventilation and deforming central airways) to global function (total lung volume) in the lung over three imaged lung volumes, to derive a breathing lung model for computational fluid dynamics simulation. The algorithm constitutes the core of an integrative, image-based computational framework for subject-specific simulation of the breathing lung. For the first time, the algorithm is applied to three multi-detector row computed tomography (MDCT) volumetric lung images of the same individual. A key technique in linking global and local variables over multiple images is an in-house mass-preserving image registration method. Throughout breathing cycles, cubic interpolation is employed to ensure

Indexed as

boundary conditionimage registrationMDCTMultiscalepulmonary air flowregional ventilation

Identifiers

PMID23794749
PMCPMC3685439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.