Evidence map›Paper›PMID 23794702›Full record

ReviewJournal of immunology (Baltimore, Md. : 1950)2013

Reciprocal relationship between myeloid-derived suppressor cells and T cells.

Srinivas Nagaraj, Je-In Youn, Dmitry I Gabrilovich

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of immunology (Baltimore, Md. : 1950), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 174 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Resolvin D2/GPR18 signaling enhances monocytic myeloid-derived suppressor cell function to mitigate abdominal aortic aneurysm formation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  5. The role and mechanism of cinnamaldehyde in cancer.Journal of food and drug analysis · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. [Advances of Immunotherapy Resistance and Coping Strategies 
in Non-small Cell Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2023
    Review
  13. Disease tolerance: a protective mechanism of lung infections.Frontiers in cellular and infection microbiology · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Srinivas NagarajDepartment of Internal Medicine, University of South Florida, Tampa, FL 33612, USA. snagaraj@health.usf.edu
Je-In Youn
Dmitry I Gabrilovich
Moffitt Cancer Center · USUniversity of South Florida · US

Funding

Correction of myeloid cell defects in cancerR01CA084488 · NCI · WISTAR INSTITUTE · PI GABRILOVICH, DMITRY I · 1999 to 2017
$5.4M
Mechanism of myeloid cell defect in cancerR01CA100062 · NCI · WISTAR INSTITUTE · PI GABRILOVICH, DMITRY I · 2004 to 2018
$4.0M
Nanomedicine Research Center Core (NRCC)P30HL101265 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI MOHAPATRA, SHYAM S · 2009 to 2010
$1.3M
NCI NIH HHS CA084488NCI NIH HHS CA100062NCI NIH HHS R01 CA084488NCI NIH HHS R01 CA100062NHLBI NIH HHS 1P30HL101265-01NHLBI NIH HHS P30 HL101265
6 · The paper itself

Abstract

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid cells that play a major role in the regulation of immune responses in many pathological conditions. These cells have a common myeloid origin, relatively immature state, common genetic and biochemical profiles, and, most importantly, the ability to inhibit immune responses. Although initial studies of MDSCs were almost exclusively performed in tumor-bearing mice or cancer patients, in recent years, it became clear that MDSCs play a critical role in the regulation of different types of inflammation that are not directly associated with cancer. In this review we discuss the nature of the complex relationship between MDSCs and the different populations of CD4(+) T cells.

Indexed as

AnimalsCD4-Positive T-LymphocytesCell CommunicationHumansInflammationMiceMonocytesMyeloid CellsNeoplasms

Identifiers

PMID23794702
PMCPMC3694485
OpenAlexW2113845760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.