Evidence map›Paper›PMID 23794006›Full record

ArticleInflammation2013

As a new inflammatory marker for familial Mediterranean fever: neutrophil-to-lymphocyte ratio.

Ahmet Ahsen, Memnune Sena Ulu, Seref Yuksel, Kasım Demir, Mukremin Uysal, Mujgan Erdogan, Gursel Acarturk

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 145 citations in OpenAlex.

  1. Trial
  2. Mean platelet volume, red cell distribution width, platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios in patients with ankylosing spondylitis and their relationships with high-frequency hearing thresholds.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
    Trial
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  6. Comorbid ADHD and Pediatric Sickle Cell Disease: Prevalence and Risk Factors.Journal of clinical psychology in medical settings · 2025
    Article
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  11. Meta-analysis of the Relationship Between Neutrophil to Lymphocyte Ratio and Nasal Polyps.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ahmet AhsenDepartment of Internal Medicine, Afyon Kocatepe University School of Medicine, Ic Hastaliklari A.D., 03200, Afyonkarahisar, Turkey, ahmetahsen@gmail.com.
Memnune Sena Ulu
Seref Yuksel
Kasım Demir
Mukremin Uysal
Mujgan Erdogan
Gursel Acarturk
Afyon Kocatepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Familial Mediterranean fever (FMF), which is an autosomal recessive disease, is characterised by recurrent febrile episodes in association with peritonitis, pleuritis and arthritis and has ongoing subclinical inflammation during attack-free period. In this study, we aimed to investigate the relationship between FMF with neutrophil-to-lymphocyte ratio (NLR), which is determined in many chronic inflammations as a new potential inflammatory mediator. We included 62 patients and 41 healthy subjects who were similar in terms of age and sex. We found that the NLR values of the patients were significantly higher than those of the control group, and C-reactive protein values were correlated with NLR. Another finding was the NLR values were significantly higher in the FMF patient with M694V mutation than with other mutations. As a result, NLR might be used in the FMF patient as an indicator of the subclinical inflammation, and the FMF patients with M694V mutation should be followed up closely because of increased subclinical inflammation risk.

Indexed as

AdultBiomarkersC-Reactive ProteinFamilial Mediterranean FeverFemaleHumansInflammationLeukocyte CountLymphocytesMaleNeutrophilsBiomarkersC-Reactive Protein

Identifiers

PMID23794006
OpenAlexW2018032838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.