Evidence map›Paper›PMID 23793973›Full record

ReviewDer Anaesthesist2013

[Basic algorithm for Point-of-Care based hemotherapy: perioperative treatment of coagulopathic patients].

C F Weber, K Zacharowski, K Brün, T Volk, E O Martin, S Hofer, S Kreuer

Registry-linked trialAbstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Anaesthesist, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03902275 (Validation of a Quantra Supported Hemotherapy Algorithm in Cardiac Surgery), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03902275 naterminatednot on this mapstarted 2019, after this paper: background citation

Validation of a Quantra Supported Hemotherapy Algorithm in Cardiac Surgery

TypeinterventionalSponsorJohann Wolfgang Goethe University HospitalRan2019 to 2020Enrolled20ConditionsHemorrhage, BleedingArmsQuantra-Algorithm, ROTEM-Algorithm
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. The thrombelastometry parameter CTEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  3. Article
  4. Review
  5. Mechanisms and aetiology-dependent treatment of acute liver failure.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  6. Review
  7. Liver failure-future challenges and remaining questions.Annals of translational medicine · 2021
    Review
  8. Article
  9. Rotational Thromboelastometry for Assessing Bleeding Complications and Factor XIII Deficiency in Cardiac Surgery Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018
    Observational
  10. Review
  11. Review
  12. [Point-of-care-based hemotherapy].Der Anaesthesist · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C F WeberKlinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt a. M., Deutschland. Christian.Weber@kgu.de
K Zacharowski
K Brün
T Volk
E O Martin
S Hofer
S Kreuer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During perioperative treatment of coagulopathic patients the so-called Point-of-Care (POC) analyses enable more rapidly available and more comprehensive hemostatic analyses compared to routinely performed conventional coagulation testing, such as activated partial thromboplastin time (aPTT), international normalized ratio (INR), fibrinogen concentration and platelet count. In this review article a hemotherapy algorithm is presented which is based on viscoelastic and aggregometric POC measurements. The algorithm was designed double sided and consists of a general and a special part. The general part contains boxes and fields for sociodemographic data and gives general recommendations for coagulation management and therapy specifications for particular patient collectives and presents proposals for emergency reversal of anticoagulation therapy. The special part refers to basic physiological conditions for hemostasis and asks for measurement results of clot initiation, clot firmness, clot stability and platelet function analyses. Reference values were defined for each parameter and therapeutic options are presented. In cases of persistent coagulopathy despite algorithm-conform therapy, the algorithm could be run through once again. Finally, the algorithm presents therapeutic options for an ultima ratio therapy approach.

Indexed as

AlgorithmsPoint-of-Care SystemsAnticoagulantsBlood CoagulationBlood Coagulation DisordersBlood Gas AnalysisEmergency Medical ServicesEvidence-Based MedicineHemostasisHemostaticsHumansInternational Normalized RatioPartial Thromboplastin TimePerioperative CarePlatelet Function TestsSocioeconomic FactorsAnticoagulantsHemostatics

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.