Evidence map›Paper›PMID 23793683›Full record

ArticleBMJ open2013

A brief intervention for drug use, sexual risk behaviours and violence prevention with vulnerable women in South Africa: a randomised trial of the Women's Health CoOp.

Wendee M Wechsberg, Rachel Jewkes, Scott P Novak, Tracy Kline, Bronwyn Myers, Felicia A Browne, Tara Carney, Antonio A Morgan Lopez, Charles Parry

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00729391 (Women-Focused HIV Prevention in the Western Cape), which is not on this map. Cited by 64 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 5 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00729391 phase2 / phase3completednot on this map

Women-Focused HIV Prevention in the Western Cape

TypeinterventionalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2008 to 2012Enrolled720ConditionsHIV, Substance Abuse, ViolenceArmsWoman-Focused Intervention (Women's Health CoOp), Nutrition (Attention-Control), VCT Only
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 5 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. HIV Risk Reduction Interventions Among Substance-Abusing Reproductive-Age Women: A Systematic Review.AIDS education and prevention : official publication of the International Society for AIDS Education · 2017
    Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Adapting an evidence-based HIV behavioral intervention for South African couples.Substance abuse treatment, prevention, and policy · 2015
    Trial
  19. Trial
  20. Trial

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Wendee M WechsbergSubstance Abuse Treatment Evaluations and Intervention Research, RTI International, Durham, North Carolina, USA.
Rachel Jewkes
Scott P Novak
Tracy Kline
Bronwyn Myers
Felicia A Browne
Tara Carney
Antonio A Morgan Lopez
Charles Parry
RTI International · USSouth African Medical Research Council · ZAHarvard University · USStellenbosch University · ZAUniversity of Cape Town · ZA

Funding

Women-Focused HIV Prevention in the Western CapeR01HD058320 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI WECHSBERG, WENDEE M · 2007 to 2011
$2.9M
NICHD NIH HHS R01 HD058320
6 · The paper itself

Abstract

objectiveTo assess the impact of the Women's Health CoOp (WHC) on drug abstinence among vulnerable women having HIV counselling and testing (HCT).

designRandomised trial conducted with multiple follow-ups.

setting15 communities in Cape Town, South Africa.

participants720 drug-using women aged 18-33, randomised to an intervention (360) or one of two control arms (181 and 179) with 91.9% retained at follow-up.

interventionsThe WHC brief peer-facilitated intervention consisted of four modules (two sessions), 2 h addressing knowledge and skills to reduce drug use, sex risk and violence; and included role-playing and rehearsal, an equal attention nutrition intervention, and an HCT-only control. PRIMARY OUTCOME MEASURES: Biologically confirmed drug abstinence measured at 12-month follow-up, sober at last sex act, condom use with main and casual sex partners, and intimate partner violence.

resultsAt the 12-month endpoint, 26.9% (n=83/309) of the women in the WHC arm were abstinent from drugs, compared with 16.9% (n=27/160) in the Nutrition arm and 20% (n=31/155) in the HCT-only control arm. In the random effects model, this translated to an effect size on the log odds scale with an OR of 1.54 (95% CI 1.07 to 2.22) comparing the WHC arm with the combined control arms. Other 12-month comparison measures between arms were non-significant for sex risk and victimisation outcomes. At 6-month follow-up, women in the WHC arm (65.9%, 197/299) were more likely to be sober at the last sex act (OR1.32 (95% CI 1.02 to 1.84)) than women in the Nutrition arm (54.3%, n=82/152).

conclusionsThis is the first trial among drug-using women in South Africa showing that a brief intervention added to HCT results in greater abstinence from drug use at 12 months and a larger percentage of sexual activity not under the influence of substances. TRIAL REGISTRATION NUMBER: NCT00729391 ClinicalTrials.gov.

Indexed as

Public Health

Identifiers

PMID23793683
PMCPMC3657672
OpenAlexW2157268154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.