Evidence map›Paper›PMID 23793558›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2013

Systematic review of microendoscopic discectomy for lumbar disc herniation.

Nick Smith, James Masters, Cyrus Jensen, Almas Khan, Andrew Sprowson

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02535273 (The Effect of Dexmedetomidine Subsidiary Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia:A Randomized, Double Blind Controlled Trial), which is not on this map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02535273 phase4unknown statusnot on this mapstarted 2015, after this paper: background citation

The Effect of Dexmedetomidine Subsidiary Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia:A Randomized, Double Blind Controlled Trial

TypeinterventionalSponsorTang-Du HospitalRan2015 to 2016Enrolled212ConditionsSpinal Diseases, Local AnesthesiaArmsDexmedetomidine, Lidocaine, Low-dose Dexmedetomidine, Moderate-dose Dexmedetomidine, High-dose Dexmedetomidine
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
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  5. A randomised controlled trial of transforaminal endoscopic discectomy vs microdiscectomy.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017
    Trial
  6. Article
  7. Review
  8. Article
  9. Use of the Zebris Ultrasonic Three-Dimensional Motion Analysis System to Evaluate Range of Motion of the Cervical Spine in 61 Healthy Adults.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
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  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nick SmithDepartment of Trauma and Orthopaedics, University Hospitals Coventry and Warwickshire, Coventry, UK, nickasmith@doctors.org.uk.
James Masters
Cyrus Jensen
Almas Khan
Andrew Sprowson
University Hospitals Coventry and Warwickshire NHS Trust · GBLeeds General Infirmary · GBWest Midlands Deanery · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSystematic review.

objectiveTo search and analyse randomised controlled trials (RCTs) published since the Cochrane review by Gibson and Waddell (2007) comparing microendoscopic discectomy (MED) with open discectomy (OD) or microdiscectomy (MD) and to assess whether MED improves patient-reported outcomes. Discectomy for symptomatic herniated lumbar discs is an effective operative treatment. A number of operative techniques exist including OD, MD, and MED. A 2007 Cochrane review identified OD as an effective treatment for symptom improvement, and found sufficient evidence for MD. However, evidence for MED was lacking.

methodsA systematic review of Medline and Embase was carried out. Aiming to identify RCTs carried out after 2007, which compared OD with MD and MED which reported the Oswestry disability index (ODI) as an outcome.

resultsFour RCTs were identified. None of the studies found a significant difference in the ODI scores between study groups at any time point. Three studies compared MED to OD and one compared OD, MD, and MED. The largest study reported an increased number of severe complications in the MED group.

conclusionsThere is some evidence to suggest that MED performed by surgeons skilled in the technique in tertiary referral centres is as effective as OD.

Indexed as

DiskectomyEndoscopyHumansIntervertebral Disc DisplacementLumbar VertebraeMicrosurgeryRandomized Controlled Trials as TopicSciaticaTreatment Outcome

Identifiers

PMID23793558
PMCPMC3886516
OpenAlexW2021184308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.