ArticleHuman genetics2013
MuPIT interactive: webserver for mapping variant positions to annotated, interactive 3D structures.
Article in Human genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
46 citing papers in PubMed.
- Leveraging transformers for semi-supervised pathogenicity prediction with soft labels.Journal of integrative bioinformatics · 2025Article
- 3DVizSNP: a tool for rapidly visualizing missense mutations identified in high throughput experiments in iCn3D.BMC bioinformatics · 2023Article
- Genetic Heterogeneity of X-Linked Ichthyosis in the Republic of North Ossetia-Alania, Case Series Report.International journal of molecular sciences · 2023Article
- VIVID: A Web Application for Variant Interpretation and Visualization in Multi-dimensional Analyses.Molecular biology and evolution · 2022Article
- Current status and future perspectives of the evaluation of missense variants by using three-dimensional structures of proteins.Biophysics and physicobiology · 2022Article
- Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism.Human genomics · 2021Article
- CDK19-related disorder results from both loss-of-function and gain-of-function de novo missense variants.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Article
- Article
- Swiss-PO: a new tool to analyze the impact of mutations on protein three-dimensional structures for precision oncology.NPJ precision oncology · 2021Article
- MCPdb: The bacterial microcompartment database.PloS one · 2021Article
- SLC12A2 variants cause a neurodevelopmental disorder or cochleovestibular defect.Brain : a journal of neurology · 2020Article
- PertInInt: An Integrative, Analytical Approach to Rapidly Uncover Cancer Driver Genes with Perturbed Interactions and Functionalities.Cell systems · 2020Article
- PsyMuKB: An Integrative De Novo Variant Knowledge Base for Developmental Disorders.Genomics, proteomics & bioinformatics · 2019Article
- PhyreRisk: A Dynamic Web Application to Bridge Genomics, Proteomics and 3D Structural Data to Guide Interpretation of Human Genetic Variants.Journal of molecular biology · 2019Article
- Stemness underpinning all steps of human colorectal cancer defines the core of effective therapeutic strategies.EBioMedicine · 2019Article
- Pathogenicity and functional impact of non-frameshifting insertion/deletion variation in the human genome.PLoS computational biology · 2019Article
- Significant abundance of cis configurations of coding variants in diploid human genomes.Nucleic acids research · 2019Article
- Cancer3D 2.0: interactive analysis of 3D patterns of cancer mutations in cancer subsets.Nucleic acids research · 2019Article
- Germline Predisposition and Copy Number Alteration in Pre-stage Lung Adenocarcinomas Presenting as Ground-Glass Nodules.Frontiers in oncology · 2019Article
- Immunogenomic Landscape Contributes to Hyperprogressive Disease after Anti-PD-1 Immunotherapy for Cancer.iScience · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Mutation position imaging toolbox (MuPIT) interactive is a browser-based application for single-nucleotide variants (SNVs), which automatically maps the genomic coordinates of SNVs onto the coordinates of available three-dimensional (3D) protein structures. The application is designed for interactive browser-based visualization of the putative functional relevance of SNVs by biologists who are not necessarily experts either in bioinformatics or protein structure. Users may submit batches of several thousand SNVs and review all protein structures that cover the SNVs, including available functional annotations such as binding sites, mutagenesis experiments, and common polymorphisms. Multiple SNVs may be mapped onto each structure, enabling 3D visualization of SNV clusters and their relationship to functionally annotated positions. We illustrate the utility of MuPIT interactive in rationalizing the impact of selected polymorphisms in the PharmGKB database, somatic mutations identified in the Cancer Genome Atlas study of invasive breast carcinomas, and rare variants identified in the exome sequencing project. MuPIT interactive is freely available for non-profit use at http://mupit.icm.jhu.edu .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.