Evidence map›Paper›PMID 23793492›Full record

ArticleJournal of materials science. Materials in medicine2013

Silver-doped self-assembling di-phenylalanine hydrogels as wound dressing biomaterials.

Federica Paladini, S T Meikle, I R Cooper, J Lacey, V Perugini, M Santin

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
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  3. Peptide-Based Materials That Exploit Metal Coordination.International journal of molecular sciences · 2022
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  12. Surface Triggered Self-Assembly of Fmoc-Tripeptide as an Antibacterial Coating.Frontiers in bioengineering and biotechnology · 2020
    Article
  13. A Novel Nanofiber Hydrogel Loaded with Platelet-Rich Plasma Promotes Wound Healing Through Enhancing the Survival of Fibroblasts.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Federica PaladiniDepartment of Engineering for Innovation, University of Salento, 73100, Lecce, Italy, federica.paladini@unisalento.it.
S T Meikle
I R Cooper
J Lacey
V Perugini
M Santin
University of Brighton · GBUniversity of Salento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic and acute wounds can be quickly contaminated and infected by microorganisms such as bacteria, multi-resistant organisms or fungi. The introduction of silver as anti-microbial agent into wound management has widely been demonstrated to be effective and contribute to wound healing. As a consequence, many approaches and different materials have been employed to synthesize antibacterial silver-hydrogels. In this work the introduction of silver particles into the fibrillar structure of self-assembling aromatic di-phenylalanine derivatives modified with aromatic groups such as 9-fluorenylmethoxycarbonyl is proposed to produce antibacterial wound dressings. Hydrogels doped with increasing amounts of silver were tested and adopted to modify flax textiles. The influence of silver on the structure of hydrogels was studied using light and confocal microscopy, while SEM-EDX allowed the characterization of the hydrogel coating on the surface of the textile substrates as well as the identification and distribution of silver nanoparticles. The antibacterial potential of the treated flax was demonstrated through microbiological tests on Staphylococcus aureus. The combination of the physico-chemical and anti-bacterial properties, together with the ease of preparation of these biomaterials, fulfils the requirement of clinically-effective wound dressings.

Indexed as

BandagesAnti-Bacterial AgentsAnti-Infective AgentsBiocompatible MaterialsBiofilmsChromatography, High Pressure LiquidFluorenesGelsHydrogelsMass SpectrometryMicroscopy, ConfocalMicroscopy, Electron, ScanningPeptidesPhenylalanineSilverSilver Compounds9-fluorenylmethoxycarbonylAnti-Bacterial AgentsAnti-Infective AgentsBiocompatible MaterialsFluorenesGelsHydrogelsPeptidesPhenylalanineSilverSilver Compounds

Identifiers

PMID23793492
OpenAlexW1971539174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.