ArticleAnnals of Saudi medicine
Risk factors for congenital hypothyroidism in Egypt: results of a population case-control study (2003-2010).
Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Spectrum of Genetic Diseases in Tunisia: Current Situation and Main Milestones Achieved.Genes · 2021Pooled it
- [Risk factors for neonatal congenital hypothyroidism: a Meta analysis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Pooled it
- Trajectories of growth and language development among children with congenital hypothyroidism concerning gender differences: Egyptian study.BMC pediatrics · 2026Article
- Analysis of Risk Factors and Screening Results of Neonatal Congenital Hypothyroidism in a Tertiary Care Center of Southern China.Journal of multidisciplinary healthcare · 2023Article
- An analysis of perinatal factors of low T3 syndrome in preterm neonates with a gestational age of 28-35 weeks.Annals of medicine · 2021Article
- Risk factors for transient and permanent congenital hypothyroidism: a population-based case-control study.Thyroid research · 2021Article
- Congenital goiter in North of Iran: A case report.Clinical case reports · 2020Article
- Trend of Congenital Hypothyroidism Incidence and Its Affecting Factors in Shahr-e-Kord, Western Iran.Iranian journal of public health · 2020Article
- [Association of related maternal factors with susceptibility to congenital hypothyroidism: a case-control study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Gender differences in risk factors of congenital hypothyroidism: an interaction hypothesis examination.International journal of endocrinology and metabolism · 2014Article
- Difference in the incidence of congenital hypothyroidism among world countries.Annals of Saudi medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesAlthough the prevention of the neuropsychological consequences of congenital hypothyroidism (CH) through the use of replacement therapy represents an important public health success, knowledge about the modifiable risk factors could reduce the number of infants affected by this disease. This study was carried out to identify risk factors for CH at Fayoum Governorate, Egypt. DESIGN AND SETTINGS: This was a population-based case-control study, which started in 2003 and was carried out for 8 years through Fayoum center of the Egyptian Ministry of Health and Population screening program for CH.
methodsThis study was a population-based case-control study carried out by using national project for CH. One control was enrolled for each new CH infant; 320 cases and 320 controls were enrolled in 8 years. Maternal and neonatal influences were investigated.
resultsA statistically significant association of CH was observed with birth defects, female gender, gestational age > 40 weeks, and gestational diabetes. An increased risk for CH was detected in twins by a multivariate analysis.
conclusionOur results suggest a multifactorial origin of CH in which genetic (high frequency of additional malformations) and environmental factors (especially maternal diabetes) play a role in the development of the disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.