Evidence map›Paper›PMID 23793157›Full record

ArticleActa crystallographica. Section D, Biological crystallography2013

Squeezing the most from every crystal: the fine details of data collection.

Tobias Krojer, Ashley C W Pike, Frank von Delft

Abstract read
In one paragraph

Article in Acta crystallographica. Section D, Biological crystallography, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. The impact of structural genomics: the first quindecennial.Journal of structural and functional genomics · 2016
    Review
  3. An overview of heavy-atom derivatization of protein crystals.Acta crystallographica. Section D, Structural biology · 2016
    Review
  4. Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing.Acta crystallographica. Section D, Structural biology · 2016
    Article
  5. Lessons from ten years of crystallization experiments at the SGC.Acta crystallographica. Section D, Structural biology · 2016
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tobias KrojerStructural Genomics Consortium, Oxford University, Roosevelt Drive, Oxford OX3 7DQ, England.
Ashley C W Pike
Frank von Delft

Funding

CIHRWellcome Trust 092809Wellcome Trust 092809/Z/10/Z
6 · The paper itself

Abstract

Modern synchrotron beamlines offer instrumentation of unprecedented quality, which in turn encourages increasingly marginal experiments, and for these, as much as ever, the ultimate success of data collection depends on the experience, but especially the care, of the experimenter. A representative set of difficult cases has been encountered at the Structural Genomics Consortium, a worldwide structural genomics initiative of which the Oxford site currently deposits three novel human structures per month. Achieving this target relies heavily on frequent visits to the Diamond Light Source, and the variety of crystal systems still demand customized data collection, diligent checks and careful planning of each experiment. Here, an overview is presented of the techniques and procedures that have been refined over the years and that are considered synchrotron best practice.

Indexed as

Computational BiologyCrystallography, X-RayData CollectionElectronic Data ProcessingGenomicsHumansMacromolecular SubstancesSynchrotronsMacromolecular Substancesdata collectiondata-collection strategystructural genomics

Identifiers

PMID23793157
PMCPMC3689534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.