Evidence map›Paper›PMID 23792711›Full record

Trial reportJournal of the International Association of Providers of AIDS Care

Effects of Lifetime History of Use of Problematic Alcohol on HIV Medication Adherence.

Aman Sharma, Ravinder Kaur Sachdeva, Mahendra Kumar, Ritu Nehra, Monika Nakra, Deborah Jones

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Aman SharmaDepartment of Internal Medicine, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India amansharma74@yahoo.com.
Ravinder Kaur SachdevaDepartment of Internal Medicine, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Mahendra KumarDepartment of Psychiatry and Neurosciences, Molecular Neuroendocrinology/Neurotransmitters Laboratories, University of Miami Miller School of Medicine, Miami, FL, USA.
Ritu NehraDepartment of Psychiatry, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Monika NakraDepartment of Internal Medicine, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Deborah JonesDepartment of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Post Graduate Institute of Medical Education and Research · INUniversity of Miami · US

Funding

Enhancing HIV Medication Adherence in IndiaR21NR011131 · NINR · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI JONES, DEBORAH LYNNE · 2009 to 2010
$374k
NINR NIH HHS R21 NR011131
6 · The paper itself

Abstract

backgroundThe effects of previous alcohol abuse on antiretroviral therapy (ART) adherence have been less studied. MATERIALS AND METHODOLOGY: Participants were randomized to a 3-month group intervention or an individual-enhanced standard-of-care condition and assessed over 6 months. Individual assessment at baseline, 3, and 6 months was done; interviews included lifetime history of problematic alcohol use.

resultsA total of 80 HIV-positive individuals on ART were recruited. In all, 35% of participants reported a history of problematic alcohol use, 37% had a detectable viral load, 55% were nonadherent, and 24% reporting skipping medication in the previous 3 months. There was no association between a history of problematic use and an adherence at any time point, that is, at baseline (t = -.7, P = .47), midpoint (t = -.39, P = .69), and 6-month follow-up (t = -1.2, P = .23).

conclusionResults suggest that a history of problematic alcohol use may not impact ART adherence.

Indexed as

AlcoholismDrug MonitoringHIV InfectionsAdultAnti-HIV AgentsFemaleHumansMaleMiddle AgedTreatment OutcomeAnti-HIV AgentsHIVlifetime historyproblematic alcohol

Identifiers

PMID23792711
PMCPMC4732521
OpenAlexW2098647383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.