Evidence map›Paper›PMID 23792697›Full record

ArticleInternational journal of environmental research and public health2013

Impact of chlorine dioxide gas sterilization on nosocomial organism viability in a hospital room.

John J Lowe, Shawn G Gibbs, Peter C Iwen, Philip W Smith, Angela L Hewlett

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Chlorine Dioxide: Friend or Foe for Cell Biomolecules? A Chemical Approach.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Low-cost, Small-scale Decontamination of Laboratory Equipment by Using Chlorine Dioxide Gas.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John J LoweDepartment of Environmental, Agricultural & Occupational Health, University of Nebraska Medical Center College of Public Health, Omaha, NE 68198, USA. jjlowe@unmc.edu.
Shawn G Gibbs
Peter C Iwen
Philip W Smith
Angela L Hewlett

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the ability of ClO2 to decontaminate pathogens known to cause healthcare-associated infections in a hospital room strains of Acinetobacter baumannii, Escherichia coli, Enterococcus faecalis, Mycobacterium smegmatis, and Staphylococcus aureus were spot placed in duplicate pairs at 10 sites throughout a hospital room and then exposed to ClO2 gas. Organisms were collected and evaluated for reduction in colony forming units following gas exposure. Six sterilization cycles with varied gas concentrations, exposure limits, and relative humidity levels were conducted. Reductions in viable organisms achieved ranged from 7 to 10-log reductions. Two sterilization cycles failed to produce complete inactivation of organisms placed in a bathroom with the door closed. Reductions of organisms in the bathroom ranged from 6-log to 10-log reductions. Gas leakage between hospital floors did not occur; however, some minor gas leakage from the door of hospital room was measured which was subsequently sealed to prevent further leakage. Novel technologies for disinfection of hospital rooms require validation and safety testing in clinical environments. Gaseous ClO2 is effective for sterilizing environmental contamination in a hospital room. Concentrations of ClO2 up to 385 ppm were safely maintained in a hospital room with enhanced environmental controls.

Indexed as

Air MicrobiologyPatients' RoomsBacteriaChlorine CompoundsColony Count, MicrobialCross InfectionDisinfectantsEnvironmental MonitoringHumansOxidesPilot ProjectsSterilizationChlorine Compoundschlorine dioxideDisinfectantsOxides

Identifiers

PMID23792697
PMCPMC3717754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.